EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.13.196 | L-ornithine + NAD(P)H + H+ + O2 |
the enzyme catalyzes the hydroxylation of L-ornithine in ferrichrome biosynthesis |
Aspergillus fumigatus |
N5-hydroxy-L-ornithine + NAD(P)+ + H2O |
- |
? |
1.14.13.196 | L-ornithine + NADH + H+ + O2 |
- |
Amycolatopsis alba |
N5-hydroxy-L-ornithine + NAD+ + H2O |
- |
? |
1.14.13.196 | L-ornithine + NADH + H+ + O2 |
first step in the biosynthesis of hydroxamate-containing siderophores, essential for virulence |
Aspergillus fumigatus |
N5-hydroxy-L-ornithine + NAD+ + H2O |
- |
? |
1.14.13.196 | L-ornithine + NADH + H+ + O2 |
the enzyme catalyzes the generation of N5-hydroxyornithine in the biosynthesis of siderophores, a reaction essential for virulence |
Aspergillus fumigatus |
N5-hydroxy-L-ornithine + NAD+ + H2O |
- |
? |
1.14.13.196 | L-ornithine + NADH + H+ + O2 |
the enzyme is essential for virulence in Aspergillus fumigatus |
Aspergillus fumigatus |
N5-hydroxy-L-ornithine + NAD+ + H2O |
- |
? |
1.14.13.196 | L-ornithine + NADH + H+ + O2 |
accepts reducing equivalents from either NADPH or NADH and displays similar kinetic parameters when using either coenzyme |
Aspergillus fumigatus |
N5-hydroxy-L-ornithine + NAD+ + H2O |
- |
? |
1.14.13.196 | L-ornithine + NADH + H+ + O2 |
AfSidA is highly specific for its amino acid substrate, only hydroxylating L-ornithine. An 8-fold preference in the catalytic efficiency is determined for NADPH compared to NADH |
Aspergillus fumigatus |
N5-hydroxy-L-ornithine + NAD+ + H2O |
- |
? |
1.14.13.196 | L-ornithine + NADPH + H+ + O2 |
- |
Amycolatopsis alba |
N5-hydroxy-L-ornithine + NADP+ + H2O |
- |
? |
1.14.13.196 | L-ornithine + NADPH + H+ + O2 |
first step in the biosynthesis of hydroxamate-containing siderophores, essential for virulence |
Aspergillus fumigatus |
N5-hydroxy-L-ornithine + NADP+ + H2O |
- |
? |
1.14.13.196 | L-ornithine + NADPH + H+ + O2 |
the enzyme catalyzes the generation of N5-hydroxyornithine in the biosynthesis of siderophores, a reaction essential for virulence |
Aspergillus fumigatus |
N5-hydroxy-L-ornithine + NADP+ + H2O |
- |
? |