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EC Number Substrates Commentary Substrates Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.45ATP + Oregon Green-labeled ubiquitin + [ubiquitin-activating protein E1]-L-cysteine enzyme efficiently accepts ubiquitin substrate fluorescently labeled by Oregon Green AMP + diphosphate + [ubiquitin-activating protein E1]-S-(Oregon Green-labeled ubiquitinyl)-L-cysteine - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.45ATP + SUMO2 + [ubiquitin-activating protein UBA5]-L-cysteine SUMO2, small ubiquitin-like modifier2, an ubiquitin-like protein AMP + diphosphate + [ubiquitin-activating protein UBA5]-S-SUMO2-L-cysteine enzyme greatly activates SUMO2 in the nucleus or transfers activated SUMO2 to the nucleus after it conjugated SUMO2 in the cytoplasm ?
Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.45ATP + ubiquitin + SUMO2 UBE1DC1 greatly activates SUMO2 in the nucleus or transfers activated-SUMO2 to nucleus after conjugation of SUMO2 in the cytoplasm ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.45ATP + ubiquitin + ubiquitin carrier protein E2 - AMP + diphosphate + ubiquitin-(ubiquitin carrier protein E2) - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.45ATP + ubiquitin + ubiquitin-fold modifier 1 - ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.45ATP + ubiquitin + Ufm1 - ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.45ATP + ubiquitin + [6His-ubiquitin-activating enzyme E1]W-8His-Strep-HA Strep, i.e.WSHPQFEK, HA, i.e. YPYDVPDYAS, under non-reducing conditions, the intermediate complex of the thioester formation is not observed without ATP AMP + diphosphate + [6His-ubiquitin-activating enzyme E1]W-8His-Strep-HA-ubiquitinyl-L-cysteine - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.45ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine E1-activating enzyme activates ubiquitin via an adenylated intermediate and catalyzes its transfer to an E2 enzyme AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.45ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine - AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.45ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine E1 activates ubiquitin or an ubiquitin-like protein and transfers it to the E2-conjugating enzyme AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine - ?
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