EC Number   |
Substrates |
Products |
Reversibility |
|---|
    4.1.1.81 | L-serine O-3-phosphate |
- |
ethanolamine-phosphate + CO2 |
- |
? |
| 4.1.1.81 | L-threonine O-3-phosphate |
- |
(R)-1-aminopropan-2-yl phosphate + CO2 |
- |
? |
| 4.1.1.81 | L-threonine O-3-phosphate |
enzyme shows stereospecificity for the L-isomer, unable to decarboxylate the D-isomer |
(R)-1-aminopropan-2-yl phosphate + CO2 |
- |
? |
| 4.1.1.81 | L-threonine O-3-phosphate |
adenosylcobalamin biosynthesis, end product of the corrin ring biosynthetic pathway is 5'-deoxyadenosylcobinamide phosphate, not 5'-deoxyadenosylcobinamide |
(R)-1-aminopropan-2-yl phosphate + CO2 |
- |
? |
| 4.1.1.81 | L-threonine O-3-phosphate |
biosynthetic pathway of cobalamin, essential cofactor for many living organisms, only synthesized de novo by bacteria and archaea |
(R)-1-aminopropan-2-yl phosphate + CO2 |
precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin |
? |
| 4.1.1.81 | L-threonine O-3-phosphate |
de novo synthesis of enzymatic cofactors, cobalamin biosynthetic pathway |
(R)-1-aminopropan-2-yl phosphate + CO2 |
precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin |
? |
| 4.1.1.81 | more |
CobD does not have lactaldehyde aminotransferase activity |
? |
- |
? |
| 4.1.1.81 | more |
bifunctional enzyme with L-threonine-O-3-phosphate decarboxylase (EC 4.1.1.81) and L-Thr kinase activities (EC 2.7.1.177). Using ATP and L-Thr as substrates, the enzyme generates ADP, L-Thr-P, and (R)-1-aminopropan-2-ol O-phosphate as products. No substrate: L-serine phosphate |
? |
- |
? |
