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EC Number	Substrates	Commentary Substrates	Products	Commentary (Products)	Reversibility
3.4.24.B11	aggrecan + H2O	several cleavage sites are determined	11 aggrecan fragment	product determination, overview	?
3.4.24.B11	aggrecan + H2O	cleavage site is Glu373-Ala374	2 aggrecan fragment	-	?
3.4.24.B11	versican isoform V0 + H2O	a second cleavage site might be Glu405-Gln406, cleavage site is Glu1428-Ala1429 in the V0 isoform, activity with recombinant and native human substrate protein	2 peptides	product identification	?
3.4.24.B11	versican isoform V1 + H2O	a second cleavage site might be Glu405-Gln406, cleavage site is Glu441-Ala442 in the V1 isoform, activity with recombinant and native human substrate protein	2 peptides	product identification	?
3.4.24.B11	thrombospondin-1 + H2O	-	36000 Da fragment + 110000 Da fragment	-	?
3.4.24.B11	thrombospondin-2 + H2O	-	42000 Da fragment + 30000 Da fragment	-	?
3.4.24.B11	aggrecan + H2O	-	?	-	?
3.4.24.B11	aggrecan + H2O	C-terminal spacer region of the enzyme is required for activity, substrate is a cartilage proteoglycan, cleavage site is the peptide bond Glu1871-Leu1872 within the substrates chondroitin sulfate attachment domain	?	-	?
3.4.24.B11	aggrecan + H2O	substrate is a cartilage proteoglycan	?	-	?
3.4.24.B11	aggrecan + H2O	in 50 mM Tris-HCl, pH 7.6, 150 mM NaCl and 5mM CaCl2 solution with 100 ng recombinant ADAMTS-1 at 37°C	?	-	?

Results 1 - 10 of 50