EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.6.1.18 | more |
development of beta-phenylalanine ester synthesis method from stable beta-keto ester substrate using engineered omega-transaminase. The omega-transaminase mutants 3FCR_4M and ATA117 11Rd show great potential for further engineering experiments aiming at the synthesis of chiral (S)- and (R)-phenylalanine esters. This alternative approach results in the conversion of 32% and 13% for the (S)- and (R)-enantiomer, respectively. Furthermore, the (S)-phenylalanine ethyl ester is isolated by performing a semi-preparative synthesis |
uncultured bacterium |
? |
- |
- |
2.6.1.18 | (R,S)-1,2-dimethylpropylamine + pyruvate |
7.5% of activity with L-beta-amino-n-butyric acid |
Achromobacter denitrificans |
3-methyl-2-oxobutane + alanine |
- |
? |
2.6.1.18 | (R,S)-1,2-dimethylpropylamine + pyruvate |
7.5% of activity with L-beta-amino-n-butyric acid |
Achromobacter denitrificans Y2k-2 |
3-methyl-2-oxobutane + alanine |
- |
? |
2.6.1.18 | (R,S)-1,5-dimethylhexylamine + pyruvate |
8.3% of activity with L-beta-amino-n-butyric acid |
Achromobacter denitrificans |
6-methyl-2-oxoheptane + alanine |
- |
? |
2.6.1.18 | (R,S)-1,5-dimethylhexylamine + pyruvate |
8.3% of activity with L-beta-amino-n-butyric acid |
Achromobacter denitrificans Y2k-2 |
6-methyl-2-oxoheptane + alanine |
- |
? |
2.6.1.18 | (R,S)-2-aminoheptane + pyruvate |
9.1% of activity with L-beta-amino-n-butyric acid |
Achromobacter denitrificans |
2-oxoheptane + alanine |
- |
? |
2.6.1.18 | (R,S)-sec-butylamine + pyruvate |
7.3% of activity with L-beta-amino-n-butyric acid |
Achromobacter denitrificans |
? + alanine |
- |
? |
2.6.1.18 | (S)-alpha-methylbenzylamine + pyruvate |
- |
Vibrio fluvialis |
acetophenone + alanine |
- |
? |
2.6.1.18 | (S)-alpha-methylbenzylamine + pyruvate |
14% of activity with L-beta-amino-n-butyric acid |
Achromobacter denitrificans |
acetophenone + alanine |
- |
? |
2.6.1.18 | (S)-alpha-methylbenzylamine + pyruvate |
- |
Vibrio fluvialis JS17 |
acetophenone + alanine |
- |
? |