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EC Number	Substrates	Commentary Substrates	Products	Commentary (Products)	Reversibility
2.4.2.17	1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate	-	ATP + 5-phospho-alpha-D-ribose 1-diphosphate	-	r
2.4.2.17	1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate	-	ATP + 5-phospho-alpha-D-ribose 1-diphosphate	-	?
2.4.2.17	ADP + 5-phospho-alpha-D-ribose 1-diphosphate	-	1-(5-phospho-beta-D-ribosyl)-ADP + diphosphate	-	r
2.4.2.17	ATP + 5-phospho-alpha-D-ribose 1-diphosphate	-	1-(5-phospho-D-ribosyl)-ATP + diphosphate	-	?
2.4.2.17	ATP + 5-phospho-alpha-D-ribose 1-diphosphate	-	1-(5-phospho-D-ribosyl)-ATP + diphosphate	-	r
2.4.2.17	ATP + 5-phospho-alpha-D-ribose 1-diphosphate	first step in histidine biosynthesis, enzyme is regulated in a complex allosterical manner, it is a key enzyme is control of the metabolic flux through the pathway	1-(5-phospho-D-ribosyl)-ATP + diphosphate	-	?
2.4.2.17	ATP + 5-phospho-alpha-D-ribose 1-diphosphate	first step in histidine biosynthesis, mechanism of regulation, overview	1-(5-phospho-D-ribosyl)-ATP + diphosphate	-	r
2.4.2.17	ATP + 5-phospho-alpha-D-ribose 1-diphosphate	first step in histidine biosynthesis	1-(5-phospho-D-ribosyl)-ATP + diphosphate	-	r
2.4.2.17	ATP + 5-phospho-alpha-D-ribose 1-diphosphate	first reaction of histidine biosynthesis	1-(5-phospho-D-ribosyl)-ATP + diphosphate	-	?
2.4.2.17	ATP + 5-phospho-alpha-D-ribose 1-diphosphate	first enzyme in histidine biosynthetic pathway. ATP-PRT expression plays a major role in regulating the pool of free His and contributes to the exceptional Ni tolerance of hyperaccumulator Alyssum species	1-(5-phospho-D-ribosyl)-ATP + diphosphate	-	?

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