EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.3.1.219 | more |
when diketide-CoA synthase (DCS) and curcumin synthase (ZoCURS) are co-incubated in the presence of 3-(4-hydroxyphenyl)propionyl-CoA and malonyl-CoA, tetrahydrobisdemethoxycurcumin and 4-hydroxybenzylacetone are produced |
Zingiber officinale |
? |
- |
- |
2.3.1.219 | (4-coumaroyl)acetyl-CoA + 4-coumaroyl-CoA + H2O |
preferred activity of CURS3 |
Curcuma longa |
bisdemethoxycurcumin + 2 CO2 + CoA |
- |
? |
2.3.1.219 | (4-coumaroyl)acetyl-CoA + 4-coumaroyl-CoA + H2O |
- |
Curcuma longa |
bisdemethoxycurcumin + CO2 + CoA |
- |
? |
2.3.1.219 | (4-coumaroyl)acetyl-CoA + feruloyl-CoA + H2O |
- |
Curcuma longa |
demethoxycurcumin + CO2 + CoA |
- |
? |
2.3.1.219 | 4-coumaroyl-CoA + (4-coumaroyl)acetyl-CoA + H2O |
curcumin synthase (ZoCURS), in the presence of diketide-CoA synthase, can accept p-coumaroyl-CoA to produce bidemethoxycurcumin |
Zingiber officinale |
2 CoA + bidemethoxycurcumin + CO2 |
- |
? |
2.3.1.219 | 4-coumaroyl-CoA + cinnamoyl-diketide-N-acetylcysteamine + H2O |
- |
Curcuma longa |
CoA + cinnamoyl-4-coumaroylmethane + N-acetylcysteamine |
- |
? |
2.3.1.219 | 4-coumaroyl-CoA + feruloylacetyl-CoA |
- |
Curcuma longa |
demethoxycurcumin + CO2 + CoA |
- |
? |
2.3.1.219 | 4-coumaroyl-CoA + feruloylacetyl-CoA |
preferred activity of CURS3 |
Curcuma longa |
demethoxycurcumin + CO2 + CoA |
- |
? |
2.3.1.219 | cinnamoyl-CoA + cinnamoyl-acetyl-CoA + H2O |
curcumin synthase (ZoCURS), in the presence of diketide-CoA synthase, can accept cinnamoyl-CoA to produce dicinnamoylmethane |
Zingiber officinale |
2 CoA + dicinnamoylmethane + CO2 |
- |
? |
2.3.1.219 | cinnamoyl-CoA + cinnamoyl-diketide-N-acetylcysteamine + H2O |
low activity |
Curcuma longa |
CoA + dicinnamoylmethane + N-acetylcysteamine |
- |
? |