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Results 1 - 8 of 8
EC Number Substrates Commentary Substrates Products Commentary (Products) Reversibility
Display the reaction diagram Show all sequences 2.1.2.B25,10-methylenetetrahydrofolate + H2O + CMP - tetrahydrofolate + 5-hydroxymethyl-CMP - ?
Display the reaction diagram Show all sequences 2.1.2.B25,10-methylenetetrahydrofolate + H2O + CMP CMP is the strongly preferred substrate over dCMP tetrahydrofolate + 5-hydroxymethyl-CMP - ?
Display the reaction diagram Show all sequences 2.1.2.B25,10-methylenetetrahydrofolate + H2O + cytidylate - tetrahydrofolate + 5-hydroxymethylcytidylate - ?
Display the reaction diagram Show all sequences 2.1.2.B25,10-methylenetetrahydrofolate + H2O + dCMP - tetrahydrofolate + 5-hydroxymethyl-dCMP - ?
Display the reaction diagram Show all sequences 2.1.2.B25,10-methylenetetrahydrofolate + H2O + deoxycytidylate - tetrahydrofolate + 5-hydroxymethyldeoxycytidylate - ?
Display the reaction diagram Show all sequences 2.1.2.B2more 5-hydroxymethylcytosine is present in a nucleoside antibiotic mildiomycin and its formation is governed by a cytidylate hydroxymethylase MilA ? - ?
Display the reaction diagram Show all sequences 2.1.2.B2more MilA uses solvent water as the hydroxyl group donor like cytidylate hydroxymethylase. Thr102 of MilA is a potential critical amino acid anchoring one molecule of water for hydroxylation. Thr102 of MilA is predicted as potential critical amino acid anchoring one molecule of water for hydroxylation ? - ?
Display the reaction diagram Show all sequences 2.1.2.B2more MilA catalyzes the conversion of CMP into 5-hydroxymethyl-CMP with an efficiency (kcat/KM) of 5fold faster than for deoxycytidylate ? - ?
Results 1 - 8 of 8