EC Number   |
Substrates |
Organism |
Products |
Reversibility  |
|---|
  2.1.1.99 | more |
hydrogenation of 2,3 double bond of tabersonine instead of hydration results in a 75% decrease in N-methylation, double bound present: no N-methylation, the presence of 6,7 double bound is a necessary structural requirement for N-methylation with membrane-bound enzyme, whereas the detergent-solubilized enzyme is also able to N-methylate the 6,7 anhydro analogue |
Catharanthus roseus |
? |
- |
? |
| 2.1.1.99 | S-adenosyl-L-methionine + 16-methoxy-2,3-dihydro-3-hydroxytabersonine |
- |
Catharanthus roseus |
S-adenosyl-L-homocysteine + deacetoxyvindoline |
i.e. N(1)-methyl-16-methoxy-2,3-dihydro-3-hydroxytabersonine |
? |
| 2.1.1.99 | S-adenosyl-L-methionine + 16-methoxy-2,3-dihydro-3-hydroxytabersonine |
high degree of specificity for the N-indole of 2,3-dihydro-3-hydroxytabersonine |
Catharanthus roseus |
S-adenosyl-L-homocysteine + deacetoxyvindoline |
- |
? |
| 2.1.1.99 | S-adenosyl-L-methionine + 16-methoxy-2,3-dihydro-3-hydroxytabersonine |
enzyme is involved in the biosynthesis of vindoline from tabersonine |
Catharanthus roseus |
S-adenosyl-L-homocysteine + deacetoxyvindoline |
- |
? |
