EC Number   |
Substrates |
Products |
Reversibility |
|---|
   2.1.1.132 | Adenosyl-L-methionine + precorrin-6Y |
- |
Adenosyl-L-homocysteine + precorrin-8X + CO2 |
- |
? |
| 2.1.1.132 | Adenosyl-L-methionine + precorrin-6Y |
enzyme of the vitamin B12 biosynthetic pathway |
? |
- |
? |
| 2.1.1.132 | Adenosyl-L-methionine + precorrin-6Y |
enzyme of the cobalamin biosynthetic pathway |
? |
- |
? |
| 2.1.1.132 | more |
the organism performs the anaerobic cobalamin biosynthesis variant, the gene cbiE of Propionibacterium freudenreichii is organized in a single ORF with genes cbiH and cbiG, overview |
? |
- |
? |
| 2.1.1.132 | more |
the organism performs the aerobic cobalamin biosynthesis variant |
? |
- |
? |
| 2.1.1.132 | more |
evolutionary origin of the cbiT |
? |
- |
? |
| 2.1.1.132 | more |
S-adenosyl-L-methionine binding structure and mechanism of CbiT |
? |
- |
? |
| 2.1.1.132 | S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+ |
methylation and decarboxylation are catalyzed by 2 different enzymes in Propionibacterium freudenreichii, encoded by gene cbiE, organized in a orf/single gene with cbiG and cbiH, which is responsible for the methylations at C5 and C15, and by gene cbiT, which is responsible for the decarboxylation, steps of the anaerobic cobalamin biosynthesis, pathway overview |
S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O |
- |
? |
| 2.1.1.132 | S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+ |
steps of the aerobic cobalamin biosynthesis, pathway overview |
S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O |
- |
? |
| 2.1.1.132 | S-adenosyl-L-methionine + cobalt-precorrin-6Y + 6 H+ |
steps of the cobalamin, i.e. vitamin B12, biosynthesis, pathway overview |
S-adenosyl-L-homocysteine + cobalt-precorrin-8X + 2 H2O |
- |
? |
