EC Number   |
Substrates |
Organism |
Products |
Reversibility  |
|---|
    1.2.1.3 | more |
enzyme LsALDH16 also exhibits esterase activity with 4-nitrophenylacetate (pNPA) as substrate in the absence of NAD+, kinetics, overview |
Loktanella sp. |
? |
- |
- |
| 1.2.1.3 | more |
no activity with hexanal, propanal, nonanal, acetaldehyde and aminoadipate semialdehyde |
Homo sapiens |
? |
- |
- |
| 1.2.1.3 | more |
to assess the degree of formaldehyde degradation, luminescence measurements in Vibrio fischeri for formaldehyde toxicity are conducted |
Saccharomyces cerevisiae |
? |
- |
- |
| 1.2.1.3 | more |
to assess the degree of formaldehyde degradation, luminescence measurements in Vibrio fischeri for formaldehyde toxicity are conducted |
Saccharomyces cerevisiae ATCC 204508 |
? |
- |
- |
| 1.2.1.3 | (2E)-4-hydroxy-2-nonenal + NAD+ + H2O |
- |
Rattus norvegicus |
(2E)-4-hydroxy-2-nonenoic acid + NADH + H+ |
- |
? |
| 1.2.1.3 | (2E)-4-hydroxy-2-nonenal + NAD+ + H2O |
- |
Bos taurus |
(2E)-4-hydroxy-2-nonenoic acid + NADH + H+ |
- |
? |
| 1.2.1.3 | (E)-2-nonenal + NAD+ + H2O |
- |
Arabidopsis thaliana |
(E)-non-2-enoate + NADH + H+ |
- |
? |
| 1.2.1.3 | (R)-N-(3-(6-(4-(1,4-dimethyl-3-oxopiperazin-2-yl)phenylamino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl)-2-methylphenyl)-4,5,6,7-tetrahydrobenzo[b] thiophene-2-carboxamide + H2O + O2 |
i.e. GDC-0834, a Bruton's tyrosine kinase inhibitor, a potential treatment of rheumatoid arthritis. GDC-0834 |
Homo sapiens |
? |
compound is extensively metabolized by amide hydrolysis by both aldehyde oxidase and carboxylesterase |
? |
| 1.2.1.3 | (R)-trans-4-hydroxy-2-nonenal + NAD+ + H2O |
- |
Rattus norvegicus |
(2E,4R)-4-hydroxynon-2-enoic acid + NADH + H+ |
- |
? |
| 1.2.1.3 | (R)-trans-4-hydroxy-2-nonenal + NAD+ + H2O |
ALDH5A enantioselectively oxidizes (R)-trans-4-hydroxy-2-nonenal |
Rattus norvegicus |
(2E,4R)-4-hydroxynon-2-enoic acid + NADH + H+ |
- |
? |
