EC Number   |
Substrates |
Products |
Reversibility |
|---|
    1.13.11.33 | (14S)-hydroperoxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid + ? |
- |
(13S,14S)-epoxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid |
- |
? |
| 1.13.11.33 | (16(R),5Z,8Z,11Z,14Z)-16-fluoroeicosa-5,8,11,14-tetraenoic acid + O2 |
- |
? |
wild-type enzyme: 78% of the 15,16(R) product and 22% of the 12,16(R) product |
? |
| 1.13.11.33 | (16(R),5Z,8Z,11Z,14Z)-16-hydroxyeicosa-5,8,11,14-tetraenoic acid + O2 |
- |
? |
wild-type enzyme and mutant enzyme I593A prouce small amounts of unspecific products. Mutant enzyme F353L produces 6% of 15,16(R) product and 94% of the 12,16(R) product |
? |
| 1.13.11.33 | (16(S),5Z,8Z,11Z,14Z)-16-fluoroeicosa-5,8,11,14-tetraenoic acid + O2 |
- |
? |
wild-type enzyme: 69% of the 15,16(S) product and 31% of the 12,16(S) product |
? |
| 1.13.11.33 | (16(S)5Z,8Z,11Z,14Z)-16-hydroxyeicosa-5,8,11,14-tetraenoic acid + O2 |
- |
? |
wild-type enzyme: 93% of the 15,16(S) product and 7% of the 12,16(S) product |
? |
| 1.13.11.33 | (17(R),5Z,8Z,11Z,14Z)-17-hydroxyeicosa-5,8,11,14-tetraenoic acid + O2 |
- |
? |
wild-type enzyme: 1% of the 15,17(R) product and 99% of the 12,17(R) product |
? |
| 1.13.11.33 | (17(S),5Z,8Z,11Z,14Z)-17-hydroxyeicosa-5,8,11,14-tetraenoic acid + O2 |
- |
? |
wild-type enzyme: 3% of the 15,17(S) product and 97% of the 12,17(S) product |
? |
| 1.13.11.33 | (18(R),5Z,8Z,11Z,14Z)-18-hydroxyeicosa-5,8,11,14-tetraenoic acid + O2 |
oxygenation proceeds with little if any enantioselectivity |
? |
- |
? |
| 1.13.11.33 | (18(S),5Z,8Z,11Z,14Z)-18-hydroxyeicosa-5,8,11,14-tetraenoic acid + O2 |
oxygenation proceeds with little if any enantioselectivity |
? |
- |
? |
| 1.13.11.33 | 1,2-diarachidonoylglycerophosphocholine + O2 |
- |
? |
- |
? |
