EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.1.1.52 | 3alpha-hydroxy-5beta-cholanate + NAD+ |
- |
Escherichia sp. |
3-oxo-5beta-cholanate + NADH |
- |
r |
1.1.1.52 | 3alpha-hydroxy-5beta-cholanate + NAD+ |
i.e. lithocholic acid |
Escherichia sp. |
3-oxo-5beta-cholanate + NADH |
- |
r |
1.1.1.52 | 3alpha-hydroxy-bis-norcholanic acid + NAD+ |
oxidation at the same rate as hydroxycholanic acid |
Escherichia sp. |
3-oxo-bis-norcholanic acid + NADH |
- |
r |
1.1.1.52 | 3alpha-hydroxy-norcholanic acid + NAD+ |
oxidation at the same rate as hydroxycholanic acid |
Escherichia sp. |
3-oxo-norcholanic acid + NADH |
- |
r |
1.1.1.52 | cholic acid + NAD+ |
oxidation at the same rate as hydroxycholanic acid |
Escherichia sp. |
7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oic acid + NADH |
- |
r |
1.1.1.52 | dehydrocholic acid + NADH |
i.e. 3,7,12-trioxocholan-24-oic acid |
Escherichia sp. |
3-hydroxy-7,12-dihydroxy-5beta-cholan-24-oic acid + NAD+ |
- |
r |
1.1.1.52 | deoxycholic acid + NAD+ |
oxidation at the same rate as hydroxycholanic acid |
Escherichia sp. |
12alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
r |
1.1.1.52 | more |
no substrates: androsterone and tetrahydrocortisone, methylation of carboxyl group or reduction to alcohol inactivates |
Escherichia sp. |
? |
- |
? |