Refine search

Search Substrates and Products (Substrate)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 55 > >>
EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
(-)-(1R,2S)-ephedrine + NAD+
-
(S)-2-methylamino-1-phenylpropan-1-one + NADH + H+
-
?
(-)-(1R,2S)-ephedrine + NAD+
the enzyme acts on a broad range of different aryl-alkyl ketones, such as haloketones, ketoamines, diketones, and ketoesters. It accepts various types of aryl groups including phenyl-, pyridyl-, thienyl-, and furyl-rings, but the presence of an aromatic ring is essential for the activity. In addition, the presence of a functional group on the alkyl chain, such as an amine, a halogen, or a ketone, is also crucial. The enzyme exhibits a strict Prelog enantioselectivity. When acting on diketones, it catalyses the reduction of only the keto group closest to the ring, with no further reduction to the diol. (-)-(1R,2S)-ephedrine i.e. (1R,2S)-1-phenyl-1-hydroxy-2-methylaminopropane. (S)-2-methylamino-1-phenylpropan-1-one i.e. (S)-methcathinone
(S)-2-methylamino-1-phenylpropan-1-one + NADH + H+
-
?
(-)-(1R,2S)-ephedrine + NAD+
the enzyme exhibits a strict enantioselectivity for the oxidation of (-)-(1R,2S)-ephedrine and (R,R)-(-)-pseudoephedrine
(S)-2-methylamino-1-phenylpropan-1-one + NADH + H+
-
?
(4-chlorophenyl)-2-pyridinylmethanone + NAD+
specifc activity: 1.74 U/mg. Product: 70% (S) enantiomeric excess
(S)-(4-chlorophenyl)(pyridin-2-yl)methanol + NADH + H+
-
?
(4-chlorophenyl)-2-pyridinylmethanone + NADH + H+
2.7% of the activity as compared to 1-phenyl-1,2-propanedione. The (R)-enantiomer is formed with 70% enantiomeric excess
(R)-(4-chlorophenyl)(pyridin-2-yl)methanol + NAD+
-
?
(R,R)-(-)-pseudoephedrine + NAD+
the enzyme exhibits a strict enantioselectivity for the oxidation of (-)-(1R,2S)-ephedrine and (R,R)-(-)-pseudoephedrine
? + NADH + H+
-
?
1,2-indandione + NAD+
specifc 50.05 U/mg
? + NADH + H+
-
?
1,2-indanedione + NADH + H+
78.1% of the activity as compared to 1-phenyl-1,2-propanedione
1-hydroxy-1,3-dihydro-2H-inden-2-one + NAD+
-
?
1,2-naphthoquinone + NAD+
specifc activity: 13.89 U/mg
? + NADH + H+
-
?
1,2-naphthoquinone + NADH + H+
21.7% of the activity as compared to 1-phenyl-1,2-propanedione
1-hydroxynaphthalen-2(1H)-one + NAD+
-
?
Results 1 - 10 of 55 > >>