EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
    1.1.1.270 | 4alpha-methylfecosterone + NADPH + H+ |
- |
Botrytis cinerea |
4alpha-methylfecosterol + NADP+ |
4alpha-methylfecosterol is further converted to ergosterol |
? |
| 1.1.1.270 | fecosterone + NADPH + H+ |
- |
Botrytis cinerea |
fecosterol + NADP+ |
- |
? |
| 1.1.1.270 | more |
substrate for 3-ketoreductase in the first sterol C-4 demethylation cycle is 4alpha-methylfecosterone, whereas that for the second C-4 demethylation cycle is fecosterone |
Botrytis cinerea |
? |
- |
? |
| 1.1.1.270 | more |
NADPH-dependent 3-ketosteroid reductase catalyzes reduction of the 3-keto group to a 3beta-hydroxyl group |
Cryptococcus neoformans |
? |
- |
? |
| 1.1.1.270 | more |
enzyme of sterol, ergosterol, biosynthesis, enzyme catalyzes last step in demethylation at C-4 |
Cryptococcus neoformans |
? |
- |
? |
| 1.1.1.270 | obtusifolione + NADPH |
4,14-dimethyl-ergosta-8,24(28)-dien-3-one |
Cryptococcus neoformans |
obtusifoliol + NADP+ |
4,14-dimethyl-ergosta-8,24(28)-dien-3-ol |
? |
| 1.1.1.270 | 3-oxocholic acid + NAD(P)H + H+ |
10.3% of the activity compared to the substrate isodeoxycholic acid |
Eggerthella sp. CAG:298 |
cholic acid + NAD(P)+ |
- |
r |
| 1.1.1.270 | 3-oxodeoxycholic acid + NAD(P)H + H+ |
55.2% of the activity compared to the substrate isodeoxycholic acid |
Eggerthella sp. CAG:298 |
isodeoxycholic acid + NAD(P)+ |
- |
r |
| 1.1.1.270 | chenodeoxycholic acid + NAD(P)+ |
11.7% of the activity compared to the substrate isodeoxycholic acid |
Eggerthella sp. CAG:298 |
3-oxo-chenodeoxycholic acid + NAD(P)H + H+ |
- |
r |
| 1.1.1.270 | cholic acid + NAD(P)+ |
12.7% of the activity compared to the substrate isodeoxycholic acid |
Eggerthella sp. CAG:298 |
3-oxo-cholic acid + NAD(P)H + H+ |
- |
r |
