EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH |
the rate-limiting step of the reaction is associated with the chemical process of transfer of the gamma-phosphate of ATP to the sulfinic acid. Two pKapp values of 6.2 and 7.5 of the bell-shaped pH-rate profile correspond to the gamma-phosphate of ATP, and to an acid-base catalyst, respectively |
Saccharomyces cerevisiae |
peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R |
- |
? |
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH |
hyperoxidized Prx1 |
Homo sapiens |
peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R |
- |
? |
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 thioredoxin |
- |
Mus musculus |
peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + thioredoxin disulfide |
- |
? |
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 thioredoxin |
- |
Arabidopsis thaliana |
peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + thioredoxin disulfide |
- |
? |
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 thioredoxin |
- |
Homo sapiens |
peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + thioredoxin disulfide |
- |
? |
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 thioredoxin |
- |
Arabidopsis thaliana Columbia |
peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + thioredoxin disulfide |
- |
? |
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + GSH |
- |
Homo sapiens |
peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + GSSG |
- |
? |
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + GSH |
- |
Rattus norvegicus |
peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + GSSG |
- |
? |
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + GSH |
identification of intact protein thiosulfinate intermediate in the reduction of cysteine sulfinic acid in peroxiredoxin by human sulfiredoxin |
Homo sapiens |
peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + GSSG |
- |
? |
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + GSH |
- |
Homo sapiens |
peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + G-S-S-G |
- |
? |