Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Substrates and Products (Substrate)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

<< < Results 11 - 20 of 137 > >>
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.27017beta-hydroxy-5alpha-androstan-3-one + NADPH DHT Mus musculus 5alpha-androstane-3beta,17beta-diol + NADP+ androstanediol ?
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.27017beta-hydroxy-5alpha-androstan-3-one + NADPH DHT Rattus norvegicus 5alpha-androstane-3beta,17beta-diol + NADP+ androstanediol ir
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.27017beta-hydroxy-5alpha-androstan-3-one + NADPH DHT Mus musculus 5alpha-androstane-3beta,17beta-diol + NADP+ 5alpha-androstane-3alpha,17beta-diol or 5alpha-androstane-3beta,17beta-diol ?
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.27017beta-hydroxy-5alpha-androstan-3-one + NADPH DHT Rattus norvegicus 5alpha-androstane-3beta,17beta-diol + NADP+ corresponding 3beta-hydroxysteroid ir
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.27017beta-hydroxy-5alpha-androstan-3-one + NADPH dihydrotestosterone Mus musculus 5alpha-androstane-3beta,17beta-diol + NADP+ androstanediol ?
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.27017beta-hydroxy-5alpha-androstan-3-one + NADPH dihydrotestosterone Rattus norvegicus 5alpha-androstane-3beta,17beta-diol + NADP+ androstanediol ir
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.27017beta-hydroxy-5alpha-androstan-3-one + NADPH dihydrotestosterone Mus musculus 5alpha-androstane-3beta,17beta-diol + NADP+ 5alpha-androstane-3alpha,17beta-diol or 5alpha-androstane-3beta,17beta-diol ?
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.27017beta-hydroxy-5alpha-androstan-3-one + NADPH dihydrotestosterone Rattus norvegicus 5alpha-androstane-3beta,17beta-diol + NADP+ corresponding 3beta-hydroxysteroid ir
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2702 17beta-hydroxy-5alpha-androstan-3-one + 2 NADPH + 2 H+ - Homo sapiens 5alpha-androstane-3beta,17beta-diol + 5alpha-androstane-3alpha,17beta-diol + 2 NADP+ the rates of 3alpha-diol versus 3beta-diol formation varies significantly among the isoforms. AKR1C1 predominantly catalyzes the formation of 3beta-diol, whereas AKR1C2 and AKR1C4 predominantly catalyze the formation of 3alpha-diol. AKR1C3 shows relatively low reductive activity towards 17beta-hydroxy-5alpha-androstan-3-one, in which 3alpha-diol and 3beta-diol is formed in almost equal amounts ?
Show all pathways known for 1.1.1.270Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2702 17beta-hydroxy-5alpha-androstan-3-one + 2 NADPH + 2 H+ AKR1cs are a source of beta-tetrahydrosteroids. This is of physiological significance because the formation of 3beta-diol in contrast to 3alpha-diol is virtually irreversible, the 3beta-diol is a pro-apoptotic ligand for estrogen receptor beta, and 3beta-tetrahydrosteroids act as gamma-aminobutyric acid type A receptor antagonists Homo sapiens 5alpha-androstane-3beta,17beta-diol + 5alpha-androstane-3alpha,17beta-diol + 2 NADP+ - ?
<< < Results 11 - 20 of 137 > >>