EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   1.1.1.105 | more |
NAD+-dependent retinoid-active SDRs have higher catalytic efficiencies for the oxidation of 3alpha-hydroxysterols than of retinols |
Homo sapiens |
? |
- |
? |
| 1.1.1.105 | more |
RDH-E2 may be involved in the pathogenesis of psoriasis through its potential role in retinoic acid biosynthesis and stimulation of keratinocyte proliferation |
Homo sapiens |
? |
- |
? |
| 1.1.1.105 | more |
RDH10 is required for proper retinoic acid signalling in the early embryo, RDH10 cooperates with retinal dehydrogenase 2 during axis development and central nervous system patterning |
Xenopus laevis |
? |
- |
? |
| 1.1.1.105 | more |
no activity is detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD+/NADH or NADP+/NADPH |
Homo sapiens |
? |
- |
? |
| 1.1.1.105 | more |
no activity with decanal |
Mus musculus |
? |
- |
? |
| 1.1.1.105 | more |
enzyme is an alcohol dehydrogenase, EC 1.1.1.1, with activity for all-trans-retinol using NAD+ as a cofactor |
Kangiella koreensis |
? |
- |
? |
| 1.1.1.105 | more |
the enzyme is not active with NADP+ or NADPH as cofactors |
Homo sapiens |
? |
- |
? |
| 1.1.1.105 | more |
in addition to all-trans-retinol, RDHE2S recognizes 11-cis-retinol as substrate |
Mus musculus |
? |
- |
- |
| 1.1.1.105 | more |
no activity toward all-trans-retinol is detected using the microsomal and mitochondrial preparations of recombinant murine RDHE2 protein expressed in Spodoptera frugiperda Sf9 cells. But although inactive toward retinol in isolated microsomes, RDHE2 is able to function as a retinol dehydrogenase in intact cells |
Mus musculus |
? |
- |
- |
| 1.1.1.105 | more |
no activity with decanal |
Mus musculus C57BL/6 x 129/Sv |
? |
- |
? |
