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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
dCTP + H2O
-
dUTP + NH3
-
?
dCTP + H2O
-
dUTP + NH3
-
?
dCTP + H2O
-
dUTP + NH3
-
?
dCTP + H2O
-
dUTP + NH3
-
?
dCTP + H2O
-
dUTP + NH3
dUMP is required for dTMP synthesis via hydrolysis of UTP by dUTPase to dUMP
?
dCTP + H2O
-
dUTP + NH3
-
?
ddCTP + H2O
deamination at the same rate as dCTP
ddUTP + NH3
-
?
dUTP + 2 H2O
-
dUMP + 2 phosphate
-
?
more
bifunctionality of enzyme avoids release of toxic UTP within cells
?
-
?
more
the bifunctional dCMP-dCTP deaminase shows dCMP deaminase and dCTP deaminase activities, dCTP serves as a positive heterotropic effector for the dCMP deaminase activity and a positive homotropic effector for the dCTP deaminase activity, and the enzymatic efficiency of the dCMP deaminase activity is about four times higher than that of the dCTP deaminase activity, the same active site is involved in both dCMP and dCTP deaminations
?
-
-
<< < Results 11 - 20 of 21 > >>