(R,S)-flurbiprofen ethyl ester + H2O
enantioselective reaction
(S)-flurbiprofen ethyl ester + (R)-flurbiprofen + ethanol
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(R,S)-flurbiprofen ethyl ester + H2O
enantioselective hydrolysis, kinetic resolution, overview
(S)-flurbiprofen + ethanol
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?
(R,S)-flurbiprofen ethyl ester + H2O
high enantiomeric excess and conversion yield of 98% and 48%, respectively
(S)-flurbiprofen + ethanol
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(R,S)-flurbiprofen ethyl ester + H2O
enantioselective hydrolysis, kinetic resolution, overview
(S)-flurbiprofen + ethanol
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?
(R,S)-ibuprofen + 1-propanol
purified enzyme in a mixture of 1-propanol-isooctane in a ratio of 3:1, the conversion of racemic ibuprofen reaches 46% with very high enantioselectivity for production of the (S)-enantiomer
(S)-ibuprofen n-propyl ester + (R)-ibuprofen
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(R,S)-ibuprofen + 1-propanol
purified enzyme in a mixture of 1-propanol-isooctane in a ratio of 3:1, the conversion of racemic ibuprofen reaches 46% with very high enantioselectivity for production of the (S)-enantiomer
(S)-ibuprofen n-propyl ester + (R)-ibuprofen
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?
(R,S)-mandelonitrile + vinyl acetate
transesterification
(S)-cyano(phenyl)methyl acetate + (R)-mandelonitrite
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(R,S)-naproxen 2,2,2-trifluoroethyl thioester
(R,S)-profen 2,2,2-trifluoroethyl thioester
(S)-naproxen + 2,2,2-trifluorothioethanol + (R)-naproxen 2,2,2-trifluoroethyl thioester
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(R,S)-[4-[4a,6b(E)]]-6-[4,4-bis(4-fluorophenyl)-3-(1-methyl-1H-tetrazol-5-yl)-1,3-butadienyl]-tetrahydro-4-hydroxy-2H-pyran-2-one + isopropenyl acetate
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(R)-(+)-[4-[4a,6b(E)]]-6-[4,4-bis(4-fluorophenyl)-3-(1-methyl-1H-tetrazol-5-yl)-1,3-butadienyl]-tetrahydro-4-hydroxy-2H-pyran-2-one + (S)-(-)-[4-[4a,6b(E)]]-6-[4,4-bis(4-fluorophenyl)-3-(1-methyl-1H-tetrazol-5-yl)-1,3-butadienyl]-tetrahydro-4-acetyloxy-2H-pyran-2-one + prop-1-en-2-ol
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?
(R/S)-ibuprofen methoxyethyl ester + H2O
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(R)-ibuprofen methoxyethyl ester + (S)-ibuprofen + 2-methoxyethanol
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