EC Number   |
Substrates |
Products |
Reversibility |
|---|
    2.7.6.2 | more |
thiamine binding site structure, overview |
? |
- |
? |
| 2.7.6.2 | ATP + thiamine |
thiamine pyrophosphokinase is required for thiamine cofactor activation in Arabidopsis |
AMP + thiamine diphosphate |
- |
? |
| 2.7.6.2 | more |
three common intronic variants in the maternal and fetal thiamine pyrophosphokinase gene (TPK1) are associated with birth weight, overview |
? |
- |
? |
| 2.7.6.2 | thiamine + ATP |
TPP plays a critical role in the carbohydrate and energy metabolism. It functions as a prosthetic group for the mitochondrial enzyme complexes like pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase and branched chain alpha-keto acid dehydrogenase. In addition, TPP is involved in the cytosolic pentose pathway functioning as coenzyme for transketolase. |
thiamine diphosphate + AMP |
- |
? |
