EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.5.1.104 | S-adenosyl 3-(methylthio)propylamine + cadaverine |
agmatine is the physiological substrate in the constitutive synthesis of spermidine, while cadaverine acts as an aminopropyl acceptor under stress conditions when an active and rapid synthesis of N-(3-aminopropyl)cadaverine could be required |
Pyrococcus furiosus |
5'-S-methyl-5'-thioadenosine + N-(3-aminopropyl)cadaverine |
- |
? |
2.5.1.104 | S-adenosyl 3-(methylthio)propylamine + homospermidine |
low activity |
Thermus thermophilus |
S-methyl-5'-thioadenosine + ? |
- |
? |
2.5.1.104 | S-adenosyl 3-(methylthio)propylamine + N,N'-bis(3-aminopropyl)-1,3-propanediamine |
i.e. thermine. Low activity |
Thermus thermophilus |
S-methyl-5'-thioadenosine + ? |
- |
? |
2.5.1.104 | S-adenosyl 3-(methylthio)propylamine + norspermidine |
- |
Thermus thermophilus |
S-methyl-5'-thioadenosine + N,N'-bis(3-aminopropyl)-1,3-propanediamine |
i.e. thermine |
? |
2.5.1.104 | S-adenosyl 3-(methylthio)propylamine + propane-1,3-diamine |
2.9% of the activity compared to cadaverine |
Pyrococcus furiosus |
5'-S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine |
- |
? |
2.5.1.104 | S-adenosyl 3-(methylthio)propylamine + putrescine |
- |
Thermococcus kodakarensis |
5'-S-methyl-5'-thioadenosine + spermidine |
- |
? |
2.5.1.104 | S-adenosyl 3-(methylthio)propylamine + putrescine |
8.7% of the activity compared to cadaverine |
Pyrococcus furiosus |
5'-S-methyl-5'-thioadenosine + spermidine |
- |
? |
2.5.1.104 | S-adenosyl 3-(methylthio)propylamine + spermidine |
0.8% of the activity compared to cadaverine |
Pyrococcus furiosus |
5'-S-methyl-5'-thioadenosine + spermine |
- |
? |
2.5.1.104 | S-adenosyl 3-(methylthio)propylamine + spermidine |
- |
Thermus thermophilus |
S-methyl-5'-thioadenosine + spermine |
no formation of thermospermine (i.e. 1,12-diamino-4,8-diazadodecane) |
? |
2.5.1.104 | S-adenosyl 3-(methylthio)propylamine + tris(3-aminopropyl)amine |
i.e. mitsubishine. Low activity. No formation of tetrakis(3-aminopropyl)ammonium |
Thermus thermophilus |
S-methyl-5'-thioadenosine + N4-aminopropylthermine |
- |
? |