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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
S-adenosyl 3-(methylthio)propylamine + cadaverine
agmatine is the physiological substrate in the constitutive synthesis of spermidine, while cadaverine acts as an aminopropyl acceptor under stress conditions when an active and rapid synthesis of N-(3-aminopropyl)cadaverine could be required
5'-S-methyl-5'-thioadenosine + N-(3-aminopropyl)cadaverine
-
?
S-adenosyl 3-(methylthio)propylamine + homospermidine
low activity
S-methyl-5'-thioadenosine + ?
-
?
S-adenosyl 3-(methylthio)propylamine + N,N'-bis(3-aminopropyl)-1,3-propanediamine
i.e. thermine. Low activity
S-methyl-5'-thioadenosine + ?
-
?
S-adenosyl 3-(methylthio)propylamine + norspermidine
-
S-methyl-5'-thioadenosine + N,N'-bis(3-aminopropyl)-1,3-propanediamine
i.e. thermine
?
S-adenosyl 3-(methylthio)propylamine + propane-1,3-diamine
2.9% of the activity compared to cadaverine
5'-S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine
-
?
S-adenosyl 3-(methylthio)propylamine + putrescine
-
5'-S-methyl-5'-thioadenosine + spermidine
-
?
S-adenosyl 3-(methylthio)propylamine + putrescine
8.7% of the activity compared to cadaverine
5'-S-methyl-5'-thioadenosine + spermidine
-
?
S-adenosyl 3-(methylthio)propylamine + spermidine
0.8% of the activity compared to cadaverine
5'-S-methyl-5'-thioadenosine + spermine
-
?
S-adenosyl 3-(methylthio)propylamine + spermidine
-
S-methyl-5'-thioadenosine + spermine
no formation of thermospermine (i.e. 1,12-diamino-4,8-diazadodecane)
?
S-adenosyl 3-(methylthio)propylamine + tris(3-aminopropyl)amine
i.e. mitsubishine. Low activity. No formation of tetrakis(3-aminopropyl)ammonium
S-methyl-5'-thioadenosine + N4-aminopropylthermine
-
?
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