5.6.1.5 | -999 |
- |
comparative proteomic analysis of wild-type cells and those lacking proteasomal function through deletion of the proteasome-activating nucleotidase PanA, reduced growth rate and cell yield of mutant strain, enriched proteins exclusive to or more abundant in the panA mutant includes cell division, dihydroxyacetone kinase-linked phosphoenolpyruvate phosphotransferase and oxidoreductase homologs, differences in transcriptional regulation and signal transduction proteins, proteasome deficiency causes an up-regulation of stress responses, components of the Fe-S cluster assembly, protein-folding, DNA binding and repair, oxidative and osmotic stress, phosphorus assimilation, and polyphosphate synthesis systems enriched in panA mutants |
692845 |