EC Number   |
Specific Activity Minimum [µmol/min/mg] |
Specific Activity Maximum [µmol/min/mg] |
Reference |
|---|
   2.7.1.136 | -999 |
- |
accessory region on plasmid pRSB111 contains a new macrolide resistance operon, mph(E) gene encodes a macrolide phosphotransferase required for high-level macrolide resistance, resistance analyzed by determining values for minimum inhibitory concentration |
690460 |
| 2.7.1.136 | -999 |
- |
genetic map of the resistance plasmid pRSB105, functional antibiotic resistance regions of plasmid pRSB105 characterized, plasmid pRSB105 harbors the macrolide resistance gene mph, encoding a macrolide 2'-phosphotransferase, transcript analysis by RT-PCR, erythromycin resistance analyzed by determining values for minimum inhibitory concentration, mph gene shown to contribute to erythromycin resistance |
690516 |
| 2.7.1.136 | -999 |
- |
substrate specificities of the mutant enzymes |
661781 |
| 2.7.1.136 | 0.0007 |
- |
purified recombinant mutant H205A, substrate oleandomycin |
661781 |
| 2.7.1.136 | 0.04 |
- |
purified recombinant wild-type enzyme, substrate roxithromycin or rokitamycin |
661781 |
| 2.7.1.136 | 0.05 |
- |
purified recombinant wild-type enzyme, substrate josamycin or tylosin |
661781 |
| 2.7.1.136 | 0.052 |
- |
purified recombinant mutant H198A, substrate oleandomycin |
661781 |
| 2.7.1.136 | 0.056 |
- |
purified recombinant mutant H205N, substrate oleandomycin |
661781 |
| 2.7.1.136 | 0.06 |
- |
purified recombinant wild-type enzyme, substrate troleandomycin, clarithromycin, azithromycin, or erythromycin |
661781 |
| 2.7.1.136 | 0.1 |
- |
purified recombinant wild-type enzyme, substrate oleandomycin |
661781 |
