EC Number |
Specific Activity Minimum [µmol/min/mg] |
Specific Activity Maximum [µmol/min/mg] |
Reference |
---|
2.1.1.1 | -999 |
- |
activity in different individuals, correlation with phenotypic differences |
441254 |
2.1.1.1 | -999 |
- |
activity in male animals of different inbred strains |
441258 |
2.1.1.1 | -999 |
- |
assay |
441252 |
2.1.1.1 | -999 |
- |
association between A/G single nucleotide polymorphism of NNMT gene and total homocysteine concentration in plasma of Japanese man analyzed, genotyping by PCR followed by melting curve analysis, NNMT genotype not determined as a strong determinant of total homocysteine concentration in plasma, modifying effect on plasma homocysteine concentration not excluded |
690123 |
2.1.1.1 | -999 |
- |
expression levels of NNMT in oral squamous cell carcinoma (OSCC), quantitative real-time PCR, Western-Blot and immunohistochemical analyses, upregulation in tumor cells, correlation between NNMT upregulation and favorable prognosis of oral squamous cell carcinoma patients |
689036 |
2.1.1.1 | -999 |
- |
quantitative enzyme activity analysis in 25 non-smalll cell lung cancer samples |
733618 |
2.1.1.1 | -999 |
- |
signal transducers and activators of transcription 3 (Stat3)-regulated genes analyzed, expression of NNMT in cancer cells, promoter activity determined after transfection experiments with NNMT promoter-luciferase reporter construct, real-time PCR, Western-Blot and immunohistochemistry, correlation between the expression of NNMT and activated Stat3 in colon cancer cells, NNMT determined as a Stat3-regulated gene and as a potential tumor marker |
687897 |
2.1.1.1 | -999 |
- |
study population, DNA analysis and allelic discrimination assay of the NNMT gene, distribution of nicotinamide N-methyltransferase genotypes in families, children carrying the NNMT A allele face additional risk of congenital heart defects (CHDs) in combination with peri-conception exposure to medicines and/or a low dietary nicotinamide intake |
686485 |
2.1.1.1 | 0.000028 |
- |
substrate 1-methyl-4-phenylpyridine, pH not specified in the publication, temperature not specified in the publication |
756932 |
2.1.1.1 | 0.0011 |
- |
Y20A mutant protein, pH 8.6, 37°C |
718914 |