EC Number |
Source Tissue |
Reference |
---|
2.3.1.135 | adipose tissue |
- |
-, 674449, 674487 |
2.3.1.135 | adrenal gland |
mRNA expression |
638619 |
2.3.1.135 | ARPE-19 cell |
- |
658661 |
2.3.1.135 | Bowman's capsule |
in the glomeruli of normal, neoplastic kidney sections |
658462 |
2.3.1.135 | brain |
mRNA expression in adult stage |
638620 |
2.3.1.135 | breast |
- |
674069 |
2.3.1.135 | breast adenocarcinoma cell |
breast carcinoma cells have lower LRAT activity |
638622 |
2.3.1.135 | breast cancer cell |
neoplastic and adjacent, non-neoplastic glandular breast tissue specimens from human patients, expression analysis, reduced enzyme expression, LRAT protein progressively decreases with a reduction in the degree of tumor differentiation in invasive breast carcinomas, overview |
674069 |
2.3.1.135 | carcinoma cell |
skin, these cells have lower LRAT activity |
638622 |
2.3.1.135 | embryo |
LRAT acts together with Cyp26A1, one of the enzymes that catalyze the degradation of retinoic acid, and possibly with STRA6, the cell surface receptor for retinol-retinol-binding protein, in maintaining adequate levels of retinoids in embryonic and extraembryonic tissues |
687788 |