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EC Number
Source Tissue
Commentary
Reference
1.1.1.B40
adenocarcinoma cell
rectum, sigmoid colon
655162
1.1.1.B40
adipocyte
-
668379
1.1.1.B40
adipose tissue
-
700178
1.1.1.B40
adipose tissue
high-fat fed animals overexpress 11beta-hydroxysteroid dehydrogenase type 2 in subcutaneous but not in retroperitoneal fat. Enzyme mRNA levels strongly correlate in both tissues with different parameters related to obesity, such as body weight, adiposity, and insulin resistance
693880
1.1.1.B40
adrenal gland
-
668432
,
670252
1.1.1.B40
aorta
-
701239
1.1.1.B40
aortic smooth muscle cell
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700178
1.1.1.B40
brain
11beta-HSD2 in the adult brain is thought to protect mineralocorticoid receptors from inactivation by corticosterone
654196
1.1.1.B40
brain
11HSD1 is highly expressed in various brain structures, including the hippocampus
743428
1.1.1.B40
brain
almost no expression and activity
695148
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