EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.105 | all-trans-retinol dehydrogenase (NAD+) |
thyroid gland |
mRNA expression |
692959 |
1.1.1.271 | GDP-L-fucose synthase |
thyroid gland |
- |
389512 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
thyroid gland |
9% mRNA expression of Rdh5 compared to liver |
690797 |
1.1.1.36 | acetoacetyl-CoA reductase |
thyroid gland |
isozyme AKR1B15.2 |
740743 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
thyroid gland |
isozyme AKR1B15.2 |
740743 |
1.1.1.71 | alcohol dehydrogenase [NAD(P)+] |
thyroid gland |
- |
655563 |
1.1.1.71 | alcohol dehydrogenase [NAD(P)+] |
thyroid gland |
highest expression |
740291 |
1.1.1.96 | diiodophenylpyruvate reductase |
thyroid gland |
- |
287554 |
1.1.5.3 | glycerol-3-phosphate dehydrogenase |
thyroid gland |
- |
-, 723350 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
thyroid gland |
- |
671327 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
thyroid gland |
parafollicular cells and follicular basement membrane |
688464 |
1.11.1.24 | thioredoxin-dependent peroxiredoxin |
thyroid gland |
0.0007 mg Prx I per mg of soluble protein Prx I, 0.0007 mg Prx II per mg of soluble protein, 0.0005 mg Prx III per mg of soluble protein, 0.0003 mg Prx V per mg of soluble protein and 0.0002 mg Prx VI per mg of soluble protein |
655756 |
1.11.1.6 | catalase |
thyroid gland |
no change in catalase activity after treatment with nicotinamide |
-, 673922 |
1.11.1.7 | peroxidase |
thyroid gland |
- |
698048 |
1.11.1.8 | iodide peroxidase |
thyroid gland |
- |
439714, 439716, 439718, 439721, 439722, 439726, 658139, 659385, 671592, 673344, 673355, 674021, 676000, 712628, 765858 |
1.11.1.8 | iodide peroxidase |
thyroid gland |
of patients with diverse thyroid diseases |
671397 |
1.11.1.8 | iodide peroxidase |
thyroid gland |
pathological tissue: Hashimotos thyroiditis, Graves disease, multinodular goiter, no activity in papillary carcinoma |
658882 |
1.11.1.8 | iodide peroxidase |
thyroid gland |
some TPO-specific T cells and the majority of autoantibodies in humans develop in response to TPO presented by thyroid cells, rather than to TPO released by damaged thyrocytes |
690126 |
1.11.1.8 | iodide peroxidase |
thyroid gland |
the molecular weight of breast TPO is slightly lower than that of thyroid TPO due to decreased glycosylation. Enzymatic activity and isoelectric point of the isomforms are comparable |
765648 |
1.11.1.8 | iodide peroxidase |
thyroid gland |
toxic diffuse goiter tissue samples obtained during thyroidectomies |
673062 |
1.11.1.8 | iodide peroxidase |
thyroid gland |
TPO activities are similar between pre-pubertal and adult female rats. Estradiol administration does not change enzyme activity in pre-pubertal rats, while in intact adults activity is increased by low or high doses of estradiol |
677145 |
1.11.1.9 | glutathione peroxidase |
thyroid gland |
- |
685441 |
1.14.13.8 | flavin-containing monooxygenase |
thyroid gland |
- |
348499 |
1.14.15.18 | calcidiol 1-monooxygenase |
thyroid gland |
- |
675192 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
thyroid gland |
- |
438390 |
1.16.98.B1 | mitochondrial amidoxime reducing component |
thyroid gland |
- |
760877 |
1.21.1.1 | iodotyrosine deiodinase |
thyroid gland |
- |
703835, 704368, 704369, 704417, 704839, 705504, 733452, 734321 |
1.21.99.4 | thyroxine 5'-deiodinase |
thyroid gland |
- |
639402, 644806, 699169, 700655, 714894 |
1.21.99.4 | thyroxine 5'-deiodinase |
thyroid gland |
after surgery |
687956 |
1.21.99.4 | thyroxine 5'-deiodinase |
thyroid gland |
isozyme type I |
644806 |
1.21.99.4 | thyroxine 5'-deiodinase |
thyroid gland |
isozyme types I and II |
644806 |
1.21.99.4 | thyroxine 5'-deiodinase |
thyroid gland |
thyronine 5'-deiodinase type I |
639406, 639408 |
1.3.1.70 | DELTA14-sterol reductase |
thyroid gland |
LBR |
672378 |
1.3.1.70 | DELTA14-sterol reductase |
thyroid gland |
TM7SF2 |
672378 |
1.4.3.1 | D-aspartate oxidase |
thyroid gland |
- |
391726 |
1.4.3.1 | D-aspartate oxidase |
thyroid gland |
with about 80 units/mg thyroid enzyme activity |
711722 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
thyroid gland |
20.3% of the activity in liver |
655483 |
1.5.1.8 | saccharopine dehydrogenase (NADP+, L-lysine-forming) |
thyroid gland |
low enzyme concentration |
392362 |
1.6.2.4 | NADPH-hemoprotein reductase |
thyroid gland |
- |
288609 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
thyroid gland |
- |
636490, 636491, 636492, 636493, 636494, 636495, 636496, 636497, 636498, 636499, 636500, 636501, 742560 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
thyroid gland |
follicular cells |
636489, 636490 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
thyroid gland |
isoform Duox2, strong expression |
671214 |
1.8.5.1 | glutathione dehydrogenase (ascorbate) |
thyroid gland |
- |
394033 |
2.1.1.13 | methionine synthase |
thyroid gland |
- |
441177 |
2.1.1.354 | [histone H3]-lysine4 N-trimethyltransferase |
thyroid gland |
- |
756801 |
2.1.1.72 | site-specific DNA-methyltransferase (adenine-specific) |
thyroid gland |
- |
719373 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
thyroid gland |
- |
676839, 757868 |
2.3.1.255 | N-terminal amino-acid Nalpha-acetyltransferase NatA |
thyroid gland |
- |
702870 |
2.3.1.37 | 5-aminolevulinate synthase |
thyroid gland |
high expression of isoform ALAS1 |
703855 |
2.3.1.B43 | protein-lysine desuccinylase (NAD+) |
thyroid gland |
- |
755970 |
2.3.2.5 | glutaminyl-peptide cyclotransferase |
thyroid gland |
- |
759702 |
2.3.2.8 | arginyltransferase |
thyroid gland |
- |
488017 |
2.4.1.17 | glucuronosyltransferase |
thyroid gland |
isozyme UGT1A7 |
659315 |
2.4.1.174 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase |
thyroid gland |
high content |
638346 |
2.4.1.174 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase |
thyroid gland |
very high content |
638345 |
2.4.1.175 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase |
thyroid gland |
high content |
638346 |
2.4.1.175 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase |
thyroid gland |
very high content |
638345 |
2.4.1.175 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase |
thyroid gland |
very low expression level |
659262 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
thyroid gland |
- |
489522 |
2.4.1.386 | GlcNAc-beta-1,3-Gal beta-1,6-N-acetylglucosaminyltransferase (distally acting) |
thyroid gland |
- |
763231 |
2.4.1.40 | glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase |
thyroid gland |
- |
489149 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
thyroid gland |
- |
719570 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
thyroid gland |
enzyme form pp-GalNAc-T15 |
658739 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
thyroid gland |
Northern blot analysis of human tissues |
659136 |
2.4.1.90 | N-acetyllactosamine synthase |
thyroid gland |
- |
489522 |
2.4.2.1 | purine-nucleoside phosphorylase |
thyroid gland |
- |
489670 |
2.4.2.26 | protein xylosyltransferase |
thyroid gland |
- |
-, 637616 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
thyroid gland |
- |
637268 |
2.4.99.18 | dolichyl-diphosphooligosaccharide-protein glycotransferase |
thyroid gland |
- |
488504 |
2.5.1.6 | methionine adenosyltransferase |
thyroid gland |
mainly MAT2beta variant 1 |
686926 |
2.6.1.16 | glutamine-fructose-6-phosphate transaminase (isomerizing) |
thyroid gland |
- |
639906 |
2.7.1.1 | hexokinase |
thyroid gland |
intermediate to high expression |
759579 |
2.7.1.11 | 6-phosphofructokinase |
thyroid gland |
- |
640421 |
2.7.1.137 | phosphatidylinositol 3-kinase |
thyroid gland |
ATCC CRTL-1486 |
688453 |
2.7.1.23 | NAD+ kinase |
thyroid gland |
- |
641202 |
2.7.1.25 | adenylyl-sulfate kinase |
thyroid gland |
PAPSS 1, 2a and 2b |
641231 |
2.7.1.52 | fucokinase |
thyroid gland |
- |
641671, 641672, 641673 |
2.7.1.8 | glucosamine kinase |
thyroid gland |
- |
642031 |
2.7.11.1 | non-specific serine/threonine protein kinase |
thyroid gland |
- |
645087 |
2.7.11.15 | beta-adrenergic-receptor kinase |
thyroid gland |
increased expression of GRK3 in hyperfunctioning thyroid nodule |
677258 |
2.7.11.16 | G-protein-coupled receptor kinase |
thyroid gland |
- |
491200 |
2.7.11.16 | G-protein-coupled receptor kinase |
thyroid gland |
increased expression of GRK4 in hyperfunctioning thyroid nodule |
677258 |
2.7.11.18 | myosin-light-chain kinase |
thyroid gland |
- |
640645 |
2.7.11.19 | phosphorylase kinase |
thyroid gland |
- |
676038 |
2.7.11.21 | polo kinase |
thyroid gland |
Plk2 |
662999 |
2.7.11.22 | cyclin-dependent kinase |
thyroid gland |
- |
491554 |
2.7.7.13 | mannose-1-phosphate guanylyltransferase |
thyroid gland |
- |
642867 |
2.7.7.41 | phosphatidate cytidylyltransferase |
thyroid gland |
weak signal |
661820 |
2.8.2.1 | aryl sulfotransferase |
thyroid gland |
activity in autoimmune thyroid disease glands is significantly higher than in normal thyroids, enzyme form SULT1A3 |
662515 |
2.8.2.1 | aryl sulfotransferase |
thyroid gland |
activity in autoimmune thyroid disease glands is significantly higher than in normal thyroids, SULT1A1 |
662515 |
2.8.2.20 | protein-tyrosine sulfotransferase |
thyroid gland |
- |
676006, 691163, 705417 |
2.8.2.20 | protein-tyrosine sulfotransferase |
thyroid gland |
TPST-2 shows higher expression as TPST-1 |
705836 |
2.8.2.21 | keratan sulfotransferase |
thyroid gland |
- |
704699 |
3.1.1.32 | phospholipase A1 |
thyroid gland |
high expression |
694548 |
3.1.1.4 | phospholipase A2 |
thyroid gland |
- |
133865 |
3.1.1.53 | sialate O-acetylesterase |
thyroid gland |
high expression level |
750708 |
3.1.2.2 | palmitoyl-CoA hydrolase |
thyroid gland |
- |
646158 |
3.1.2.20 | acyl-CoA hydrolase |
thyroid gland |
- |
646158 |
3.1.3.16 | protein-serine/threonine phosphatase |
thyroid gland |
- |
654407 |
3.1.3.48 | protein-tyrosine-phosphatase |
thyroid gland |
- |
694827 |