EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.13.11.31 | arachidonate 12-lipoxygenase |
pineal gland |
- |
395427 |
1.14.16.4 | tryptophan 5-monooxygenase |
pineal gland |
- |
438654, 438660, 688281, 688765 |
1.14.16.4 | tryptophan 5-monooxygenase |
pineal gland |
TPH1 |
657881, 689062 |
1.21.99.4 | thyroxine 5'-deiodinase |
pineal gland |
isozyme type II |
644806 |
1.21.99.4 | thyroxine 5'-deiodinase |
pineal gland |
thyronine 5'-deiodinase type II |
639409, 639416 |
1.4.3.1 | D-aspartate oxidase |
pineal gland |
- |
712818, 743140 |
1.4.3.1 | D-aspartate oxidase |
pineal gland |
D-Asp content in the adult rat pineal gland is very high, especially in the distal (caudal) region of the gland, little staining is found in the proximal (rostral) region |
711719 |
1.4.3.4 | monoamine oxidase |
pineal gland |
MAOA activity and gene expression is upregulated in different brain areas of Alzheimer's disease patients, including the pineal gland. Increased pineal MAOA activity might contribute to the reduced pineal melatonin production in Alzheimer's disease. Alzheimer's disease patients carrying long MAOA-VNTR genotype (consisting of 3.5- or 4-repeat alleles) show higher MAOA gene expression and activity than the short-genotyped Alzheimer's disease patients (i.e., 3-repeat allele). MAOA-VNTR affects the activity and gene expression of MAOA in the brain of Alzheimer's disease patients, and is involved in the changes of monoamine metabolism |
685879 |
2.1.1.4 | acetylserotonin O-methyltransferase |
pineal gland |
- |
-, 441479, 441481, 441482, 441483, 441484, 441486, 441487, 441488, 441490, 441491, 441492, 441493, 441495, 441498, 661910, 699789, 719307, 734508, 756897 |
2.1.1.4 | acetylserotonin O-methyltransferase |
pineal gland |
not surrounding areas |
441480 |
2.1.1.4 | acetylserotonin O-methyltransferase |
pineal gland |
pineal parenchymal cell tumor |
720294 |
2.3.1.5 | arylamine N-acetyltransferase |
pineal gland |
- |
-, 487105, 487107, 487111, 487123, 487126, 487627, 487628 |
2.3.1.87 | aralkylamine N-acetyltransferase |
pineal gland |
- |
487105, 487126, 487621, 487622, 487624, 487627, 487628, 487629, 487632, 658812, 659760, 660381, 675525, 702214, 704421, 720470, 736686 |
2.3.1.87 | aralkylamine N-acetyltransferase |
pineal gland |
4fold increase at night |
487633 |
2.3.1.87 | aralkylamine N-acetyltransferase |
pineal gland |
exposure of dark-adapted animals to near ultraviolet light significantly decreases melatonin content and the activity of serotonin N-acetyltransferase |
676177 |
2.3.1.87 | aralkylamine N-acetyltransferase |
pineal gland |
from fish in different phases of the annual breeding cycle, and pineal organ culture |
719583 |
2.3.1.87 | aralkylamine N-acetyltransferase |
pineal gland |
inducible |
-, 487123 |
2.3.1.87 | aralkylamine N-acetyltransferase |
pineal gland |
photoreceptor cells, enzyme activity is regulated by circadian system, the photoperiodic control is direct in fish and frogs and indirect in mammals. Structural and functional evolution of the melatonin-producing units in vertebrates, overview |
701705 |
2.3.1.87 | aralkylamine N-acetyltransferase |
pineal gland |
pineal gland-specific isozyme AANAT2 is specifically expressed in pineal opsin-immunoreactive photoreceptor cells, developmental expression pattern, s significant 60fold reduction in Aanat2 expression occurs just before metamorphosis, overview |
703833 |
2.3.1.87 | aralkylamine N-acetyltransferase |
pineal gland |
rhythmic expression of adenylyl cyclase VI contributes to the differential regulation of serotonin N-acetyltransferase by bradykinin in rat pineal glands |
674501 |
2.3.1.87 | aralkylamine N-acetyltransferase |
pineal gland |
the enzyme catalyzes the first step in melatonin biosynthesis, melatonin biosynthesis follows a day and night rhythm, which is different in fasted, fed, and refed fish, overview |
703832 |
2.3.1.87 | aralkylamine N-acetyltransferase |
pineal gland |
transcripts are detected almost exclusively in the pineal gland |
736685 |
2.5.1.6 | methionine adenosyltransferase |
pineal gland |
at night, 2.5fold increase of activity of isoform MAT II |
659509 |
2.7.11.13 | protein kinase C |
pineal gland |
- |
659760 |
2.7.11.14 | rhodopsin kinase |
pineal gland |
- |
491015, 640717, 640720, 640730 |
2.7.11.14 | rhodopsin kinase |
pineal gland |
adult, expression of RK |
491015 |
2.7.11.14 | rhodopsin kinase |
pineal gland |
contains RK mRNA |
490996 |
2.7.11.14 | rhodopsin kinase |
pineal gland |
expression of retinal GRK1 |
640720, 640723 |
2.7.11.14 | rhodopsin kinase |
pineal gland |
GRK1 expression |
640730 |
2.7.11.14 | rhodopsin kinase |
pineal gland |
GRK1B and GRK7-2 are the dominant subtypes |
675527 |
2.7.11.14 | rhodopsin kinase |
pineal gland |
young and adult |
640720 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
pineal gland |
- |
666110 |
2.7.11.25 | mitogen-activated protein kinase kinase kinase |
pineal gland |
- |
762367 |
2.7.7.41 | phosphatidate cytidylyltransferase |
pineal gland |
- |
643325 |
3.1.3.108 | nocturnin |
pineal gland |
minimal expression |
755768 |
3.4.11.3 | cystinyl aminopeptidase |
pineal gland |
- |
753121 |
3.4.11.7 | glutamyl aminopeptidase |
pineal gland |
- |
699650 |
4.1.1.28 | aromatic-L-amino-acid decarboxylase |
pineal gland |
- |
4200, 4222, 4227 |
4.6.1.1 | adenylate cyclase |
pineal gland |
AC6 |
679659 |
5.1.1.13 | aspartate racemase |
pineal gland |
- |
728034 |