EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.21 | aldose reductase |
myocardium |
- |
667205, 668540 |
1.1.1.211 | long-chain-3-hydroxyacyl-CoA dehydrogenase |
myocardium |
- |
741474 |
1.1.1.37 | malate dehydrogenase |
myocardium |
activity decreases 2.7times in myocardium of rats with experimental ischemia. Ischemic tissue damage is accompanied by changes in activity and kinetic and regulatory characteristics of cytoplasmic NAD-MDH from rat heart. It probably results from conformational changes in the enzyme molecule during generation and activation of reactive oxygen species of free radical processes |
668125 |
1.14.13.8 | flavin-containing monooxygenase |
myocardium |
FMO1, expression profiling in tissue from patients with atrial fibrillation |
686276 |
1.14.15.3 | alkane 1-monooxygenase |
myocardium |
- |
671219 |
1.2.1.104 | pyruvate dehydrogenase system |
myocardium |
- |
656580 |
1.2.1.105 | 2-oxoglutarate dehydrogenase system |
myocardium |
- |
656580 |
1.2.1.3 | aldehyde dehydrogenase (NAD+) |
myocardium |
- |
711691 |
1.21.99.3 | thyroxine 5-deiodinase |
myocardium |
healthy and infarcted |
686408 |
1.21.99.4 | thyroxine 5'-deiodinase |
myocardium |
- |
714664 |
1.21.99.4 | thyroxine 5'-deiodinase |
myocardium |
thyronine 5'-deiodinase type I |
639414 |
1.3.5.1 | succinate dehydrogenase |
myocardium |
- |
656605 |
1.3.8.8 | long-chain acyl-CoA dehydrogenase |
myocardium |
- |
671584 |
1.4.3.13 | protein-lysine 6-oxidase |
myocardium |
- |
698212 |
1.6.1.2 | NAD(P)+ transhydrogenase (Re/Si-specific) |
myocardium |
- |
711287 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
myocardium |
- |
710816 |
2.1.1.28 | phenylethanolamine N-methyltransferase |
myocardium |
- |
677224 |
2.1.1.357 | [histone H3]-lysine36 N-dimethyltransferase |
myocardium |
- |
754243 |
2.3.1.97 | glycylpeptide N-tetradecanoyltransferase |
myocardium |
increased in the myocardium of ischemia-reperfusion rat model myocardium. Rats with mild or no detectable Parkinson syndrome features on rotenone show slight but insignificantly increased activity. Rats with moderately severe Parkinson syndrome features have higher level of NMT activity, which is borderline significant compared to controls. Rats with severe PS features had the highest NMT activity which is significantly greater compared to controls and to the rats with equivocal or no motor slowing |
674059 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
myocardium |
in the mouse model of coronary ligation, modulation of FXIII activity by therapy impacts myocardial healing |
686486 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
myocardium |
transglutaminase factor XIII levels are diminished in patients after infarct rupture. Transglutaminase factor XIII activity peaks on day 3 after myocardial infarction |
686486 |
2.3.3.10 | hydroxymethylglutaryl-CoA synthase |
myocardium |
- |
-, 488102 |
2.4.99.20 | 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase |
myocardium |
- |
724210 |
2.7.1.107 | diacylglycerol kinase (ATP) |
myocardium |
- |
702437 |
2.7.1.137 | phosphatidylinositol 3-kinase |
myocardium |
isozyme phosphatidylinositol 3-kinase gamma |
-, 708146 |
2.7.1.91 | sphingosine kinase |
myocardium |
- |
672942 |
2.7.11.15 | beta-adrenergic-receptor kinase |
myocardium |
- |
661499, 661502, 662730 |
2.7.11.15 | beta-adrenergic-receptor kinase |
myocardium |
myocardial G protein-coupled receptor kinase expression and activity, overview |
684461 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
myocardium |
- |
491281, 740328 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
myocardium |
isozyme CaMKIIdelta splicing variants deltaB and deltaC |
664537 |
2.7.11.18 | myosin-light-chain kinase |
myocardium |
- |
675068 |
2.7.11.18 | myosin-light-chain kinase |
myocardium |
adult, MLCK occurs in a cross-striated pattern overlapping with the distribution of alpha-actin |
672981 |
2.7.11.18 | myosin-light-chain kinase |
myocardium |
expression analysis, overview |
687922 |
2.7.11.19 | phosphorylase kinase |
myocardium |
postmortem tissue, 8fold increase in glycogen concentration and no detectable phosphorylase kinase activity |
694549 |
2.7.11.24 | mitogen-activated protein kinase |
myocardium |
the MAPK family enzymes have regulatory function in the myocardium |
666322 |
2.7.12.2 | mitogen-activated protein kinase kinase |
myocardium |
- |
679655 |
2.7.3.2 | creatine kinase |
myocardium |
- |
762027 |
2.7.8.1 | ethanolaminephosphotransferase |
myocardium |
- |
644408, 644413 |
2.8.3.5 | 3-oxoacid CoA-transferase |
myocardium |
- |
645988 |
3.1.1.4 | phospholipase A2 |
myocardium |
sPLA2 present in the limits of the infarcted myocardium |
708252 |
3.1.1.67 | fatty-acyl-ethyl-ester synthase |
myocardium |
- |
646064 |
3.1.1.67 | fatty-acyl-ethyl-ester synthase |
myocardium |
2 enzymes accounting for 19% and 81% of the total fatty acid ethyl ester synthetic capability |
646063 |
3.1.1.67 | fatty-acyl-ethyl-ester synthase |
myocardium |
enzyme with FAEES/carboxylesterase activity, structurally different from synthase I-III |
646079 |
3.1.1.67 | fatty-acyl-ethyl-ester synthase |
myocardium |
FAEES-III, one of 3 human myocardial forms |
646069 |
3.1.1.67 | fatty-acyl-ethyl-ester synthase |
myocardium |
ventricular |
646062, 646063, 646065, 646079 |
3.1.2.2 | palmitoyl-CoA hydrolase |
myocardium |
- |
646149 |
3.1.2.20 | acyl-CoA hydrolase |
myocardium |
- |
646149 |
3.1.2.20 | acyl-CoA hydrolase |
myocardium |
WY-14643 dramatically induces myocardial cte1 expression |
671244 |
3.1.3.17 | [phosphorylase] phosphatase |
myocardium |
- |
94690 |
3.1.3.4 | phosphatidate phosphatase |
myocardium |
- |
677543 |
3.1.3.4 | phosphatidate phosphatase |
myocardium |
isozyme PAP-2 |
677543 |
3.1.3.4 | phosphatidate phosphatase |
myocardium |
isozymes PAP-1 and PAP-2 |
677543 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
myocardium |
- |
669403 |
3.1.4.4 | phospholipase D |
myocardium |
- |
652960 |
3.1.4.4 | phospholipase D |
myocardium |
atrial |
666094 |
3.3.2.10 | soluble epoxide hydrolase |
myocardium |
- |
695484, 700360, 709563, 709564 |
3.4.15.1 | peptidyl-dipeptidase A |
myocardium |
- |
710097 |
3.4.17.23 | angiotensin-converting enzyme 2 |
myocardium |
- |
708649, 708684 |
3.4.21.108 | HtrA2 peptidase |
myocardium |
- |
668267 |
3.4.21.118 | kallikrein 8 |
myocardium |
KLK8 expression is upregulated in left ventricle of cardiac hypertrophy models |
755463 |
3.4.21.39 | chymase |
myocardium |
- |
695395 |
3.4.21.B12 | prostase |
myocardium |
- |
680174 |
3.4.22.43 | cathepsin V |
myocardium |
- |
753828 |
3.4.22.53 | calpain-2 |
myocardium |
- |
687653 |
3.4.24.35 | gelatinase B |
myocardium |
- |
697147, 700147 |
3.4.24.56 | insulysin |
myocardium |
- |
696530 |
3.4.24.7 | interstitial collagenase |
myocardium |
- |
708143 |
3.4.24.7 | interstitial collagenase |
myocardium |
expression profile of MMPs/TIMP-1 after myocardial infarction, angiotensin II receptor blockade improves MMPs/TIMP-1 balance, overview |
707376 |
3.4.24.80 | membrane-type matrix metalloproteinase-1 |
myocardium |
- |
677477 |
3.4.24.80 | membrane-type matrix metalloproteinase-1 |
myocardium |
ischemic and nonischemic remote myocardium |
668265 |
3.5.1.23 | ceramidase |
myocardium |
- |
711799 |
3.5.1.99 | fatty acid amide hydrolase |
myocardium |
- |
-, 719538 |
3.5.3.18 | dimethylargininase |
myocardium |
- |
667155, 697624 |
3.5.4.6 | AMP deaminase |
myocardium |
- |
757444 |
3.6.5.2 | small monomeric GTPase |
myocardium |
- |
720356 |
4.1.1.9 | malonyl-CoA decarboxylase |
myocardium |
- |
679449, 747464 |
4.2.1.3 | aconitate hydratase |
myocardium |
- |
33815, 696162 |
4.4.1.1 | cystathionine gamma-lyase |
myocardium |
- |
709212 |
4.6.1.2 | guanylate cyclase |
myocardium |
- |
714819 |
5.3.4.1 | protein disulfide-isomerase |
myocardium |
- |
701629 |
5.3.99.2 | Prostaglandin-D synthase |
myocardium |
auricle, ventricle |
702057 |
6.2.1.1 | acetate-CoA ligase |
myocardium |
- |
581 |
6.2.1.3 | long-chain-fatty-acid-CoA ligase |
myocardium |
- |
671244 |
7.1.1.2 | NADH:ubiquinone reductase (H+-translocating) |
myocardium |
- |
693532 |
7.1.1.9 | cytochrome-c oxidase |
myocardium |
- |
691048 |
7.2.2.13 | Na+/K+-exchanging ATPase |
myocardium |
ventricular |
695856 |
7.2.2.3 | P-type Na+ transporter |
myocardium |
- |
747446 |