1.8.1.9 | thioredoxin-disulfide reductase |
mesothelioma cell line |
quantification of the expression of alternative mRNA forms (alpha1/2, alpha6, alpha7/8, alpha10/11, alpha13, gamma2-4, and beta1) in six different human malignant mesothelioma cell lines of epithelioid (STAV-AB and M-14-K), sarcomatoid (STAV-FCS and ZL34), or mixed phenotype (M-28-K and M-9-K). The lowest level of TrxR1 is seen for the two sarcomatoid forms (STAV-FCS and ZL34), whereas the epithelioid phenotypes generally show very high levels of TrxR1. The major transcript form expressed in all cell lines is alpha1/2, followed by alpha7/8. The lowest level is observed for alpha6, which comprises less than 1% of the total a forms |
686324 |