EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
cerebral cortex |
- |
763094 |
1.1.1.153 | sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) |
cerebral cortex |
- |
761589 |
1.1.1.153 | sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) |
cerebral cortex |
pyramidal neurons |
655138 |
1.1.1.178 | 3-hydroxy-2-methylbutyryl-CoA dehydrogenase |
cerebral cortex |
- |
673530 |
1.1.1.188 | prostaglandin-F synthase |
cerebral cortex |
- |
389457 |
1.1.1.21 | aldose reductase |
cerebral cortex |
- |
-, 739113 |
1.1.1.211 | long-chain-3-hydroxyacyl-CoA dehydrogenase |
cerebral cortex |
- |
-, 740102 |
1.1.1.278 | 3beta-hydroxy-5alpha-steroid dehydrogenase |
cerebral cortex |
activity below detection limit of 0.1 fmol/mg protein/min |
639089 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
cerebral cortex |
5% mRNA expression of Rdh5 compared to liver |
690797 |
1.1.1.357 | 3alpha-hydroxysteroid 3-dehydrogenase |
cerebral cortex |
- |
763094 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
cerebral cortex |
moderate expression |
685803 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
cerebral cortex |
- |
-, 765297 |
1.11.1.9 | glutathione peroxidase |
cerebral cortex |
- |
686868 |
1.13.11.34 | arachidonate 5-lipoxygenase |
cerebral cortex |
- |
-, 689167 |
1.14.11.67 | [histone H3]-trimethyl-L-lysine4 demethylase |
cerebral cortex |
- |
-, 713122 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
cerebral cortex |
- |
440224, 686293, 700433 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
cerebral cortex |
- |
686269 |
1.14.14.25 | cholesterol 24-hydroxylase |
cerebral cortex |
- |
735877 |
1.14.14.25 | cholesterol 24-hydroxylase |
cerebral cortex |
pyramidal neurons |
687987 |
1.14.15.4 | steroid 11beta-monooxygenase |
cerebral cortex |
- |
688009 |
1.14.16.2 | tyrosine 3-monooxygenase |
cerebral cortex |
- |
695603 |
1.14.16.2 | tyrosine 3-monooxygenase |
cerebral cortex |
developing, intereurons, the majority of cortical tyrosine hydroxylase cells at all ages contains phosphorylated tyrosine hydroxylase |
685887 |
1.14.16.5 | alkylglycerol monooxygenase |
cerebral cortex |
- |
688220 |
1.14.17.1 | dopamine beta-monooxygenase |
cerebral cortex |
- |
727633 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
cerebral cortex |
- |
686417 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
cerebral cortex |
PGHS-2 has highest abundance in hippocampus and cerebral cortex |
698086 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
cerebral cortex |
PGSHS-1 has highest abundance in hippocampus and cerebral cortex |
698086 |
1.16.3.1 | ferroxidase |
cerebral cortex |
- |
689209 |
1.17.1.4 | xanthine dehydrogenase |
cerebral cortex |
- |
644557, 644558 |
1.17.1.4 | xanthine dehydrogenase |
cerebral cortex |
high rate of dehydrogenase activity |
644557, 644558 |
1.2.1.105 | 2-oxoglutarate dehydrogenase system |
cerebral cortex |
- |
673870, 762740 |
1.2.1.12 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) |
cerebral cortex |
- |
656594 |
1.2.1.25 | branched-chain alpha-keto acid dehydrogenase system |
cerebral cortex |
- |
763513 |
1.2.3.1 | aldehyde oxidase |
cerebral cortex |
- |
390422 |
1.2.4.4 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) |
cerebral cortex |
- |
725082 |
1.21.99.3 | thyroxine 5-deiodinase |
cerebral cortex |
isozyme type III |
644796, 644798 |
1.3.1.24 | biliverdin reductase |
cerebral cortex |
- |
725769 |
1.3.5.1 | succinate dehydrogenase |
cerebral cortex |
- |
686054 |
1.3.5.2 | dihydroorotate dehydrogenase (quinone) |
cerebral cortex |
high enzyme level |
713150 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
cerebral cortex |
prefrontal, expression of isozymes 5alpha-R1 and 5alpha-R2 |
655526 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
cerebral cortex |
- |
762783 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
cerebral cortex |
high expression in astrocytes, low expression in neurons |
712431 |
1.4.3.1 | D-aspartate oxidase |
cerebral cortex |
- |
743140 |
1.4.3.1 | D-aspartate oxidase |
cerebral cortex |
relatively high enzyme expression just after birth, the content gradually decreases thereafter |
711719 |
1.4.3.13 | protein-lysine 6-oxidase |
cerebral cortex |
LOX on the surface of pyramidal cells in the grey matter, LOXL in the nuclei of cortex cells and in the cytosol of capillary endothelial cells |
659751 |
1.4.3.3 | D-amino-acid oxidase |
cerebral cortex |
- |
699164, 723921, 742603 |
1.4.3.4 | monoamine oxidase |
cerebral cortex |
environmentally relevant concentrations of Hg may influence the activities of ChE and MAO in the cerebral cortex |
687025 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
cerebral cortex |
25.9% of the activity in liver |
655483 |
1.6.1.2 | NAD(P)+ transhydrogenase (Re/Si-specific) |
cerebral cortex |
- |
658473 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
cerebral cortex |
cortical culture |
689225 |
1.6.99.1 | NADPH dehydrogenase |
cerebral cortex |
- |
392796 |
1.6.99.1 | NADPH dehydrogenase |
cerebral cortex |
distribution of NADPH-diaphorase activity in different human cortical areas, remarkable laminar and interareal differences across areas |
672837 |
2.1.1.202 | multisite-specific tRNA:(cytosine-C5)-methyltransferase |
cerebral cortex |
reduction of upper-layer neurons in the Nsun2 -/- cortex, mouse brain cortex at E18.5 showing the location of the indicated markers |
758477 |
2.1.1.5 | betaine-homocysteine S-methyltransferase |
cerebral cortex |
BHMT expression is observed in the amygdala of basal ganglia and the cerebral cortex where BHMT levels are clearly elevated during torpor |
735112 |
2.1.1.6 | catechol O-methyltransferase |
cerebral cortex |
membrane-bound COMT activities in the cerebral cortex are significantly reduced in high-salt loaded Dahl salt-sensitive rats compared with normal-salt loaded Dahl salt-sensitive rats |
685455 |
2.2.1.1 | transketolase |
cerebral cortex |
thiamine-deficinet diet reduces transketolase activity in both cortex and hippocampus, without significantly affecting the activities of pyruvate dehydrogenase, alpha-ketoglutamate dehydrogenase, and glucose 6-phosphate dehydrogenase |
699663 |
2.3.1.105 | alkylglycerophosphate 2-O-acetyltransferase |
cerebral cortex |
- |
486104, 486105 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
cerebral cortex |
anterior and posterior |
755989 |
2.3.1.50 | serine C-palmitoyltransferase |
cerebral cortex |
- |
487177 |
2.3.1.6 | choline O-acetyltransferase |
cerebral cortex |
- |
736678 |
2.3.1.61 | dihydrolipoyllysine-residue succinyltransferase |
cerebral cortex |
- |
487343 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
cerebral cortex |
- |
487384, 487393 |
2.3.1.7 | carnitine O-acetyltransferase |
cerebral cortex |
strong activity |
720292 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
cerebral cortex |
- |
-, 758981 |
2.3.2.27 | RING-type E3 ubiquitin transferase |
cerebral cortex |
- |
690750 |
2.3.2.5 | glutaminyl-peptide cyclotransferase |
cerebral cortex |
- |
758904 |
2.3.3.1 | citrate (Si)-synthase |
cerebral cortex |
- |
702966 |
2.4.1.174 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase |
cerebral cortex |
- |
638345 |
2.4.1.175 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase |
cerebral cortex |
- |
638345, 659262 |
2.4.1.206 | lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase |
cerebral cortex |
fetal |
638232, 638235 |
2.4.1.206 | lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase |
cerebral cortex |
not adult |
638235 |
2.4.1.214 | glycoprotein 3-alpha-L-fucosyltransferase |
cerebral cortex |
- |
661837 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
cerebral cortex |
- |
687078 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
cerebral cortex |
- |
658240 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
cerebral cortex |
enzyme form pp-GalNAc-T15 |
658739 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
cerebral cortex |
- |
637272 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
cerebral cortex |
- |
639661, 723273, 759644, 760219 |
2.5.1.16 | spermidine synthase |
cerebral cortex |
highest levels of expression in nucleus accumbens, taenia tecta, cerebellar cortex, cerebral cortical layer I, hippocampus, hypothalamus, mesencephalic raphe nuclei, central and lateral amygdala, and the circumventricular organs. Distinct presence in mossy fiber terminals of cerebellar cortex |
688510 |
2.6.1.19 | 4-aminobutyrate-2-oxoglutarate transaminase |
cerebral cortex |
- |
738349 |
2.6.1.42 | branched-chain-amino-acid transaminase |
cerebral cortex |
- |
673846 |
2.6.1.64 | glutamine-phenylpyruvate transaminase |
cerebral cortex |
- |
-, 759850 |
2.7.1.1 | hexokinase |
cerebral cortex |
- |
723652 |
2.7.1.1 | hexokinase |
cerebral cortex |
the contribution of glucokinase to total glucose-phosphorylating activity is of 15.3% in the cerebral cortex |
705268 |
2.7.1.107 | diacylglycerol kinase (ATP) |
cerebral cortex |
- |
640358, 640386 |
2.7.1.149 | 1-phosphatidylinositol-5-phosphate 4-kinase |
cerebral cortex |
isoform PI5P4Kbeta is expressed in neuronal populations, especially hippocampus and cortex |
759554 |
2.7.1.20 | adenosine kinase |
cerebral cortex |
- |
676193 |
2.7.1.40 | pyruvate kinase |
cerebral cortex |
- |
661404, 661406 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
cerebral cortex |
- |
738165 |
2.7.11.1 | non-specific serine/threonine protein kinase |
cerebral cortex |
expression of CK1epsilon-3 |
662955 |
2.7.11.1 | non-specific serine/threonine protein kinase |
cerebral cortex |
MAST3 shows selective expression in striatum and cortex as determined by in situ hybridization |
691552 |
2.7.11.12 | cGMP-dependent protein kinase |
cerebral cortex |
predominant expression of isozyme cGKIbeta |
662962 |
2.7.11.13 | protein kinase C |
cerebral cortex |
- |
725768 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebral cortex |
- |
490911, 640698, 640709, 645000, 645003, 645005 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebral cortex |
brain: highest beta-ARK mRNA concentrations in cerebral cortex and cerebellum |
490985 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebral cortex |
highest beta-ARK activity |
645001 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
cerebral cortex |
- |
694396, 694403, 705904, 761014 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
cerebral cortex |
cerebral cortical neuronal nucleus |
694382 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
cerebral cortex |
isozymes CaMKIdelta and CaMKIalpha |
676188 |
2.7.11.2 | [pyruvate dehydrogenase (acetyl-transferring)] kinase |
cerebral cortex |
- |
642132 |
2.7.11.22 | cyclin-dependent kinase |
cerebral cortex |
- |
662124, 662688, 664179, 666467, 695204 |