EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
HaCaT cell |
- |
740159 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
HaCaT cell |
- |
760802 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
HaCaT cell |
- |
285997 |
1.1.1.44 | phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) |
HaCaT cell |
- |
741037 |
1.13.11.31 | arachidonate 12-lipoxygenase |
HaCaT cell |
- |
703699 |
1.13.11.33 | arachidonate 15-lipoxygenase |
HaCaT cell |
- |
703699 |
1.13.11.53 | acireductone dioxygenase (Ni2+-requiring) |
HaCaT cell |
- |
764226 |
1.14.11.68 | [histone H3]-trimethyl-L-lysine27 demethylase |
HaCaT cell |
- |
745509 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
HaCaT cell |
- |
689252 |
1.14.15.18 | calcidiol 1-monooxygenase |
HaCaT cell |
- |
695625 |
1.17.3.2 | xanthine oxidase |
HaCaT cell |
- |
686881 |
1.21.99.3 | thyroxine 5-deiodinase |
HaCaT cell |
human keratinocyte cell line |
689755 |
1.3.1.21 | 7-dehydrocholesterol reductase |
HaCaT cell |
- |
740913 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
HaCaT cell |
- |
762902 |
1.3.1.24 | biliverdin reductase |
HaCaT cell |
- |
711662 |
1.3.1.48 | 13,14-dehydro-15-oxoprostaglandin 13-reductase |
HaCaT cell |
- |
746356 |
1.3.5.1 | succinate dehydrogenase |
HaCaT cell |
- |
741795 |
1.3.5.2 | dihydroorotate dehydrogenase (quinone) |
HaCaT cell |
premalignant |
712071 |
1.5.3.17 | non-specific polyamine oxidase |
HaCaT cell |
- |
764224 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
HaCaT cell |
keratinocyte |
688206 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
HaCaT cell |
keratinocyte cell line. Long-term survival mechanisms in niacin deficient cells involve accumulation of reactive oxygen species and increased DNA damage with concomitant increase in expression and activity of NAD(P)H oxidase |
686880 |
1.8.4.11 | peptide-methionine (S)-S-oxide reductase |
HaCaT cell |
primary keratinocytes, expression level at normal light and UV-light conditions |
669752 |
2.1.1.6 | catechol O-methyltransferase |
HaCaT cell |
- |
734847 |
2.3.1.135 | phosphatidylcholine-retinol O-acyltransferase |
HaCaT cell |
- |
715720 |
2.3.1.5 | arylamine N-acetyltransferase |
HaCaT cell |
- |
757699 |
2.3.1.50 | serine C-palmitoyltransferase |
HaCaT cell |
- |
702560 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
HaCaT cell |
- |
718564 |
2.4.1.212 | hyaluronan synthase |
HaCaT cell |
- |
690807, 693592, 736064, 736219 |
2.4.2.3 | uridine phosphorylase |
HaCaT cell |
- |
674032 |
2.4.2.4 | thymidine phosphorylase |
HaCaT cell |
- |
674032 |
2.7.1.137 | phosphatidylinositol 3-kinase |
HaCaT cell |
- |
687266 |
2.7.1.36 | mevalonate kinase |
HaCaT cell |
- |
759158 |
2.7.1.91 | sphingosine kinase |
HaCaT cell |
- |
704989 |
2.7.10.1 | receptor protein-tyrosine kinase |
HaCaT cell |
- |
703980 |
2.7.11.1 | non-specific serine/threonine protein kinase |
HaCaT cell |
- |
693189 |
2.7.11.10 | IkappaB kinase |
HaCaT cell |
- |
691676 |
2.7.11.24 | mitogen-activated protein kinase |
HaCaT cell |
- |
740938 |
2.7.11.24 | mitogen-activated protein kinase |
HaCaT cell |
spontaneously immortalized keratinocyte cell line |
663830 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
HaCaT cell |
- |
693151 |
2.7.3.2 | creatine kinase |
HaCaT cell |
expresses low levels of cytoplasmic, high levels of mitochondrial creatine kinase. Targeting the dominating isoform by its siRNA has strong effect on overall enzyme activity. Inhibition of mitochondrial isoform causes a strong decline in cell viability and cell proliferation and also substantial alteration of mitochondrial morphology as well as mitochondrial membrane topology |
675957 |
2.7.3.2 | creatine kinase |
HaCaT cell |
HaCaT cells express low levels of cytoplasmic creatine kinase (BB-CK) and high levels of mitochondrial creatine kinase (uMiCK). HeLa-S3 cells express high levels of cytoplasmic creatine kinase (BB-CK) and low levels of mitochondrial creatine kinase (uMiCK) |
675957 |
2.7.4.14 | UMP/CMP kinase |
HaCaT cell |
cidofovir-resistant tumour cell line, no infection with human papilloma virus |
739215 |
3.1.1.1 | carboxylesterase |
HaCaT cell |
keratinocyte, high abundance of isoform hCE2, but not hCE1 |
678552 |
3.2.1.143 | poly(ADP-ribose) glycohydrolase |
HaCaT cell |
- |
732765 |
3.2.2.27 | uracil-DNA glycosylase |
HaCaT cell |
- |
692963 |
3.3.2.6 | leukotriene-A4 hydrolase |
HaCaT cell |
- |
753158 |
3.4.11.2 | membrane alanyl aminopeptidase |
HaCaT cell |
keratinocyte cell line, high activity |
663842 |
3.4.21.105 | rhomboid protease |
HaCaT cell |
- |
717957 |
3.4.21.109 | matriptase |
HaCaT cell |
- |
755095, 755167 |
3.4.21.118 | kallikrein 8 |
HaCaT cell |
- |
707907 |
3.4.21.20 | cathepsin G |
HaCaT cell |
- |
753400 |
3.4.21.73 | u-Plasminogen activator |
HaCaT cell |
- |
698349 |
3.4.21.75 | Furin |
HaCaT cell |
- |
700627 |
3.4.21.B39 | stratum corneum tryptic enzyme |
HaCaT cell |
- |
717412 |
3.4.21.B40 | kallikrein 9 |
HaCaT cell |
- |
752721 |
3.4.21.B6 | prostasin |
HaCaT cell |
- |
709134, 755167 |
3.4.22.1 | cathepsin B |
HaCaT cell |
- |
679629 |
3.4.22.27 | cathepsin S |
HaCaT cell |
- |
668394 |
3.4.22.40 | bleomycin hydrolase |
HaCaT cell |
- |
731954 |
3.4.22.52 | calpain-1 |
HaCaT cell |
- |
708745 |
3.4.22.56 | caspase-3 |
HaCaT cell |
- |
699212 |
3.4.22.57 | caspase-4 |
HaCaT cell |
- |
731612 |
3.4.23.5 | cathepsin D |
HaCaT cell |
- |
711855 |
3.4.24.18 | meprin A |
HaCaT cell |
- |
688204 |
3.4.24.22 | stromelysin 2 |
HaCaT cell |
keratinocyte cell line, induction of enzyme and matrix metalloproteinases MMP-1 and MMP-3 by UVA, induction is suppressed by beta-carotene. beta-Carotene dose-dependently quenches 1O2-mediated induction of enzyme and MMP-1 |
668695 |
3.4.24.7 | interstitial collagenase |
HaCaT cell |
immortalized human keratinocyte cells |
709591 |
3.4.24.81 | ADAM10 endopeptidase |
HaCaT cell |
- |
752713 |
3.4.24.B9 | ADAM9 endopeptidase |
HaCaT cell |
- |
680831 |
4.1.1.22 | histidine decarboxylase |
HaCaT cell |
- |
747438 |
4.1.2.13 | fructose-bisphosphate aldolase |
HaCaT cell |
- |
704838 |
4.2.99.18 | DNA-(apurinic or apyrimidinic site) lyase |
HaCaT cell |
- |
704948 |
5.3.99.3 | prostaglandin-E synthase |
HaCaT cell |
- |
670732 |
6.4.1.2 | acetyl-CoA carboxylase |
HaCaT cell |
- |
693151 |