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EC Number Renatured (Commentary) Reference
Show all pathways known for 2.5.1.48Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.48unfolding by guanidinium/HCl inactivates the enzyme due to loss of ketoenamine tautomer. Though pyridoxal 5'-phosphate induces difference in secondary structure content, it is unable to provide stabilizing effect during the overall secondary structure unfolding process. It induces tertiary structure stability of the protein thereby counteracting the deleterious effect of denaturant 704053
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