EC Number |
kcat/KM Value [1/mMs-1] |
kcat/KM Value Maximum [1/mMs-1] |
Substrate |
Reference |
---|
4.2.1.22 | 0.0006 |
- |
L-cysteine |
formation of (2R,2'R)-3,3'-sulfanediylbis(2-aminopropanoic acid), mutant E223G, pH 7.5, 37°C |
749243 |
4.2.1.22 | 0.005 |
- |
L-cystathionine |
reverse reaction (L-cystathionine hydrolysis), mutant S289A |
702457 |
4.2.1.22 | 0.031 |
- |
L-serine |
mutant S289A |
702457 |
4.2.1.22 | 0.07 |
- |
H2S |
cosubstrate L-serine, pH 7.4, 37°C |
746768 |
4.2.1.22 | 0.12 |
- |
L-cysteine |
formation of (2R,2'R)-3,3'-sulfanediylbis(2-aminopropanoic acid), wild-type, pH 7.5, 37°C |
749243 |
4.2.1.22 | 0.13 |
- |
L-cysteine |
cosubstrate H2O, pH 7.4, 37°C |
746768 |
4.2.1.22 | 0.15 |
- |
L-homocysteine |
formation of L-cystathionine, mutant A70S, pH 7.5, 37°C |
749243 |
4.2.1.22 | 0.17 |
- |
H2S |
cosubstrate L-serine, presence of S-adenosyl-L-methionine, pH 7.4, 37°C |
746768 |
4.2.1.22 | 0.18 |
- |
L-cysteine |
cosubstrate H2O, presence of S-adenosyl-L-methionine, pH 7.4, 37°C |
746768 |
4.2.1.22 | 0.28 |
- |
L-serine |
cosubstrate H2S, pH 7.4, 37°C |
746768 |