EC Number |
kcat/KM Value [1/mMs-1] |
kcat/KM Value Maximum [1/mMs-1] |
Substrate |
Reference |
---|
3.1.1.84 | 0.0005 |
- |
6-monoacetylmorphine |
recombinant enzyme, pH 7.4, 37°C |
750291 |
3.1.1.84 | 0.013 |
- |
heroin |
recombinant enzyme, pH 7.4, 37°C |
750291 |
3.1.1.84 | 15.17 |
- |
(-)-cocaine |
wild type enzyme, at 25°C, in 0.1 M potassium phosphate, pH 7.5 |
714702 |
3.1.1.84 | 15.17 |
- |
(-)-cocaine |
wild type enzyme, pH not specified in the publication, at 25°C |
714226, 716278 |
3.1.1.84 | 141.7 |
- |
(-)-cocaine |
mutant enzyme A328W/Y332A, pH not specified in the publication, at 25°C |
714226 |
3.1.1.84 | 233.3 |
- |
(-)-cocaine |
mutant enzyme A328W/Y332G, pH not specified in the publication, at 25°C |
714226 |
3.1.1.84 | 516.7 |
- |
(-)-cocaine |
mutant enzyme F227A/S287G/A328W/Y332M, pH not specified in the publication, at 25°C |
714226 |
3.1.1.84 | 702 |
- |
cocaine |
mutant enzyme LMWP-T172R/G173Q, at pH 7.4 and 37°C |
730421 |
3.1.1.84 | 823 |
- |
cocaine |
mutant enzyme YGRKKRRQRRR-T172R/G173Q, at pH 7.4 and 37°C |
730421 |
3.1.1.84 | 847 |
- |
cocaine |
mutant enzyme T172R/G173Q -LMWP, at pH 7.4 and 37°C |
730421 |