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EC Number General Information Commentary Reference
Show all pathways known for 6.3.2.10Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.10metabolism MurF is the enzyme responsible for the last step in the biosynthesis of UDP-N-acetylmuramyl-pentapeptide, the monomeric precursor of peptidoglycan -, 743956
Show all pathways known for 6.3.2.10Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.10physiological function MurF adds D-Ala-D-Ala dipeptide to UDP-N-acetylmuramyl-L-Ala-c-D-Glu-m-DAP (or L-Lys) in an ATP-dependent manner, which is the last step in the biosynthesis of monomeric precursor of peptidoglycan for bacterial cell wall synthesis -, 744222
Show all pathways known for 6.3.2.10Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.10physiological function MurF is the enzyme responsible for the last step in the biosynthesis of UDP-N-acetylmuramyl-pentapeptide, the monomeric precursor of peptidoglycan. MurF catalyzes the addition of D-Ala-D-Ala dipeptide to UDP-N-acetylmuramyl-tripeptide [UDPMurNAc-L-Ala-gamma-D-Glu-m-DAP(or L-Lys)] in an ATP-dependent manner. The gamma-phosphate of ATP is transferred to the C-terminal carboxylate of UDP-N-acetylmuramyl-tripeptide to form an acyl phosphate intermediate, which is subsequently attacked by the amino group of the incoming dipeptide to form a peptide bond in a non-ribosomal fashion -, 743956
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