EC Number   |
General Information |
Reference |
|---|
    5.1.99.4 | malfunction |
alpha-methylacyl coenzyme A racemase is positive in most cancers and dysplasias but only rarely in nonneoplastic epithelium |
703973 |
| 5.1.99.4 | malfunction |
overexpression of alpha-methylacyl-CoA racemase is associated with CTNNB1 mutations in hepatocellular carcinomas |
727604 |
| 5.1.99.4 | metabolism |
beta-oxidation of branched-chain fatty acids, important enzyme for the metabolism of branched-chain lipids and drugs |
706046 |
| 5.1.99.4 | metabolism |
beta-oxidation pathway of fatty acids |
701681 |
| 5.1.99.4 | physiological function |
alpha-methylacyl-CoA racemase catalyses the inversion of configuration at the 2-position of fatty acyl-CoA esters from 2R to 2S and controls entry of metabolites into peroxisomal beta-oxidation |
706046 |
| 5.1.99.4 | physiological function |
alpha-methylacyl-CoA racemase is a protein that plays an important role in mitochondrial and peroxisomal beta-oxidation of branched-chain fatty acid and bile acid intermediates |
704836 |
| 5.1.99.4 | physiological function |
AMACR is involved in the beta-oxidation of the dietary branched-chain fatty acids and bile acid intermediate |
727322 |
| 5.1.99.4 | physiological function |
enzyme catalyzes the 1,1-proton transfer reaction that effects the reversible epimerization of the coenzyme A thioesters derived from a variety of (2R)- and (2S)-methyl branched fatty acids |
701681 |
| 5.1.99.4 | physiological function |
enzyme catalyzes the racemization of alpha-methyl carboxylic coenzyme A thioesters in mitochondria and peroxisomes, induction of AMACR-specific cytotoxic mononuclear cells from prostate cancer patients peripheral blood mononuclear cells |
705416 |
| 5.1.99.4 | physiological function |
enzyme is involved in the beta-oxidation of branched-chain fatty acids |
703387 |
