EC Number   |
General Information |
Reference |
|---|
   4.2.1.30 | evolution |
glycerol dehydratase is functionally characterised to two main groups, one is the vitamin B12-dependent and the other the B12-independent. Glycerol dehydratase evolutionary history and analysis of the functional residues responsible for type I divergence, enzyme phylogenetic tree topology with two clades, one for vitamin B12-dependent and the other for B12-independent class, overview |
-, 714387 |
| 4.2.1.30 | malfunction |
GDH loses most of its beta-subunit after purification by either ion exchange chromatography or using a nickel chelate column |
702830 |
| 4.2.1.30 | metabolism |
3-hydroxypropionic acid production pathway from glycerol |
746602 |
| 4.2.1.30 | metabolism |
GDHt is the key enzyme and catalyzes the rate limiting step for biotransformation from glycerol to 1,3-propanediol |
-, 713813 |
| 4.2.1.30 | metabolism |
glycerol dehydratase catalyses glycerol reductive conversion to 3-hydroxypropanaldehyde, the first step required for the microbial conversion of glycerol to 1,3-propanodiol |
-, 714387 |
| 4.2.1.30 | metabolism |
the enzyme is involved in the 3-hydroxypropionic acid biosynthetic pathway |
748579 |
| 4.2.1.30 | physiological function |
overexpressed glycerol dehydratase shows higher enzyme activity than that of wild-strain |
-, 705190 |
| 4.2.1.30 | physiological function |
radical S-adenosyl-L-methionine activation of the B12-independent glycerol dehydratase results in formation of 5-deoxy-5-(methylthio)adenosine and not 5-deoxyadenosine |
714252 |
| 4.2.1.30 | physiological function |
recombinant Escherichia coli strain HMS174(DE3)/pCOLADuet-1::dhaB1B2::pduP::phaC1 can accumulate poly(3-hydroxypropionate) at up to 11.98% of the cell dry weight |
701830 |
