EC Number   |
General Information |
Reference |
|---|
   4.1.1.2 | evolution |
oxalate decarboxylase belongs to the low-pH-inducible cupin superfamily of enzymes |
728524 |
| 4.1.1.2 | more |
analysis of transport of the product, i.e., CO2, from the reaction center to the surface of the enzyme using atomistic molecular dynamics simulations. Structure-function analysis using protein crystal structure, PDB ID 1L3J, simulations, overview. Domain I is the active site domain, while domain II is nonreceptive to hosting the formate and is incapable of releasing the CO2 molecule |
728195 |
| 4.1.1.2 | more |
the conformational properties of an active-site loop segment, defined by residues Ser161-Glu162-Asn163-Ser164, are important for modulating the intrinsic reactivity of Mn(II) in the active site of Bacillus subtilis oxalate decarboxylase. O2 might participate as a reversible electron sink in two putative proton-coupled electron transfer steps and is not merely used to generate a protein-based radical or oxidized metal center. The conserved Arg/Thr hydrogen bond is important for correctly locating the side chain of Glu162, which mediates a proton-coupled electron transfer step prior to decarboxylation in the catalytically competent form of the enzyme |
-, 726979 |
| 4.1.1.2 | more |
the enzyme is involved in resistance against oxalate- and Nep1-like protein-producing pathogens in plants. Oxalic acid and Nep1-like proteins are recognized as elicitors of programmed cell death in plants, which is crucial for the pathogenic success of necrotrophic plant pathogens and involves reactive oxygen species |
728346 |
| 4.1.1.2 | physiological function |
enzyme expression in Glycine max and Lathyrus sativus improves seed quality and tolerance to the fungal pathogen Sclerotinia sclerotiorum |
748902 |
| 4.1.1.2 | physiological function |
rats artificially colonized by recombinant Lactobacillus plantarum expressing and secreting heterologous oxalate decarboxylase show reduced urinary oxalate excretion therby preventing renal calcium oxalate stone deposition |
748244 |
