EC Number   |
General Information |
Reference |
|---|
   3.5.1.29 | metabolism |
AAMS amidohydrolase is involved in a degradation pathway of vitamin B6 (final step in degradation pathway I of vitamin B6) |
710733 |
| 3.5.1.29 | metabolism |
binding of (E)-2-(acetamidomethylene)succinate to the enzyme is crucial for biological function of the enzyme and the last step reaction of vitamin B6 biological degradation |
735080 |
| 3.5.1.29 | metabolism |
the enzyme catalyzes the final reaction in the degradation of vitamin B6 |
711220 |
| 3.5.1.29 | more |
molecular docking of the two substrate isomers E- and Z-2-(acetamidomethylene)succinate to the hydrolase, molecular dynamics simulations and calculations of binding free energies, usage of X-ray crystal structure of E-2AMS hydrolase, PDB ID 3KXP, overview |
735080 |
| 3.5.1.29 | physiological function |
binding of (E)-2-(acetamidomethylene)succinate to the enzyme is crucial for biological function of the enzyme and the last step reaction of vitamin B6 biological degradation |
735080 |
