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3.4.23.40
metabolism
either the plant-specific insert domain or the C-terminal peptide VGFAEAA is necessary and sufficient to direct proteins to the vacuole. Both domains are vacuolar sorting determinants
734915
3.4.23.40
physiological function
epithelial A549 cell-bound cardosin A is internalized to endosomes and lysosomes and triggers the permeability of lysosomal membrane leading to apoptosis of the epithelial cells. The enzyme may have a defensive function against the ingestion of cardoon flowers by human, insects, and other herbivores
755355
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