EC Number   |
General Information |
Reference |
|---|
   3.4.21.49 | more |
identification of the DNA binding sites of the enzyme using an electrophoretic mobility shift asay |
731590 |
| 3.4.21.49 | physiological function |
hypodermin C does not modulate the production of the cytokines interleukin-10, interleukin-4, or interferon-gamma |
710194 |
| 3.4.21.49 | physiological function |
hypodermin C protease degrades the guinea pig complement C3, and inhibits the complement pathway in vitro, immunosuppressive effect of hypodermin C on complement component 3 in vitro, the cytotoxicity of C3 is inhibited in cultures of stably transfected COS7 cells expressing the enzyme |
731590 |
| 3.4.21.49 | physiological function |
the enzyme is involved in the larval migration in the tissue and prevents the activation of the host immune response. The enzyme displays an immunosuppressive effect on complement component 3 in vitro |
753170 |
