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EC Number General Information Commentary Reference
Show all pathways known for 3.3.2.7Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.7physiological function hepoxilins (HXs) and trioxilins (TrXs) are involved in physiological processes such as inflammation, insulin secretion and pain perception in human. They are metabolites of polyunsaturated fatty acids (PUFAs), including arachidonic acid, eicosapentaenoic acid and docosahexaenoic acid, formed by 12-lipoxygenase (LOX) and epoxide hydrolase (EH) expressed by mammalian cells. Hepoxilin epoxide hydrolase converts hepoxilins into trioxilins through hydrolysis of the epoxy group 754847
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