EC Number   |
General Information |
Reference |
|---|
    3.2.2.9 | malfunction |
single MTN1 or MTN2 knock down mutants do not display an obvious morphological phenotype when grown on sulfur sufficient media or on soil, mtn1-1/mtn2-1 double mutant plants display delayed flowering, produce underdeveloped siliques, and are sterile |
716534 |
| 3.2.2.9 | metabolism |
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase plays a key role in the methionine-recycling pathway of bacteria and plants |
709718 |
| 3.2.2.9 | physiological function |
5'-methylthioadenosine nucleosidase is a crucial enzyme of the Yang cycle |
716534 |
| 3.2.2.9 | physiological function |
deletion of the SAHN gene abolishes the production of the quorum sensing signal AI-2 and biofilm formation |
751486 |
| 3.2.2.9 | physiological function |
MtnN is not required for the development of a mature biofilm. Deletion of MtnN encoding methylthioadenosine/S-adenosylhomocysteine nucleosidase does not prevent biofilm development. Two independent mtnN mutants exhibit diminished growth rate and motility in swarm agar plates |
-, 749799 |
| 3.2.2.9 | physiological function |
the enzyme is essential for the virulence of Staphylococcus aureus and contributes to sepsis infection of mice. The enzyme is not essential for growth under nutrient-rich conditions, but is essential for autoinducer-2 production |
-, 727637 |
| 3.2.2.9 | physiological function |
the enzyme is involved in the synthesis of 4,5-dihdroxy-2,3-pentanedione from methionine. S-adenosyl-L-homocysteine hydrolysis by MTA/SAH nucleosidase yields S-(5-deoxy-D-ribos-5-yl)-L-homocysteine, a precursor of autoinducer-2 synthesis, a quorum-sensing signal that governs a variety of bacterial phenotypes such as virulence and biofilm formation |
716263 |
| 3.2.2.9 | physiological function |
the enzyme plays key roles in S-adenosylmethionine recycling, the biosynthesis of autoinducer molecules, and the biosynthesis of menaquinone |
-, 715607 |
