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3.2.1.169
malfunction
enzyme knockout mice show nearly complete perinatal lethality associated with low circulating glucose and low liver glycogen stores. Enzyme loss leads to defects in metabolic homeostasis culminating in obesity and insulin resistance
751058
3.2.1.169
malfunction
enzyme loss in Drosophila globally impacts the epigenetic machinery allowing N-acetyl-D-glucosamine accumulation on RNA polymerase II and numerous chromatin factors including TRX, ASH1, and SET1
751087
3.2.1.169
metabolism
caspase-3 efficiently cleaved O-GlcNAcase
704403
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