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Results 1 - 5 of 5
EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.167evolution the enzyme belongs to the glycoside hydrolase family 30, GH30, subfamily 3 -, 731207
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.167metabolism the central precursor metabolite of wogonin and baicalein and their glycosylated forms is chrysin 753230
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.167physiological function relationship between contents of principal flavones in hairy roots of Scutellaria baicalensis with the activity of the beta-glucuronidase (sGUS) enzyme during a culturing cycle. The enzyme activity is characterized by significant and reasonable correlation only with the wogonin contents. The endogenous beta-glucuronidase (sGUS), that catalyzes the cleavage of the glucuronic acid residue from the glycosylated forms of phenolic compounds 753230
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.167physiological function the beta-glucuronidase enzyme is involved in the formation of the more active aglycone flavones in the mdicinal plant. The enzyme activity is characterized by significant correlation only with the wogonin contents, whereas the correlation for the baicalin is insignificant 753230
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.167physiological function the protective effect of baicalin (the main active compound in Scutellariae radix (Huangqin)) against aminoacetophen (APAP or paracetamol)-induced hepatotoxicity is not altered through enzyme inhibition by D-saccharic acid 1.4-lactone. SAL, a beta-glucuronidase inhibitor, strongly decreased the intestinal beta-glucuronidase activity in mice, but the baicalin-provided protection against APAP-induced cytotoxicity in L-02 cells is not altered after the application of SAL, thus protection of baicalin against APAP-induced hepatotoxicity does not require the conversion into its aglycone baicalein 752730
Results 1 - 5 of 5