EC Number   |
General Information |
Reference |
|---|
  3.13.1.4 | evolution |
the apoenzyme structure shows that AcdDPN7 belongs to the acyl-CoA dehydrogenase superfamily fold |
-, 733012 |
| 3.13.1.4 | metabolism |
the enzyme catalyzes the key step in the the 3,3'-dithiodipropionic acid (DTDP) catabolic pathway, overview |
-, 733012 |
| 3.13.1.4 | more |
Arg84 is a key residue in the desulfination reaction, the guanidinium group of the arginine is essential for desulfination, modelling of the enzyme-substrate complex, overview. Structure-function analysis and active site structure determination, modeling of substrate binding. The Arg84, Asp88 and Gln246 side chains and the isoalloxazine ring of FAD define the enzymatic environment for the desulfination reaction |
-, 733012 |
| 3.13.1.4 | physiological function |
the enzyme catalyzes sulfur abstraction from 3-sulfinopropionyl-CoA, a key step during the catabolism of 3,3'-dithiodipropionic acid |
-, 733012 |
| 3.13.1.4 | physiological function |
the enzyme is responsilbe for the final defulfination step during catabolism of 3,3'-dithiopropionate, a sulfur-containing substrate for biosynthensis of polythioesters, the final reaction before propionyl-CoA enters the central metabolism on the level of the methylcitric acid cycle |
-, 725282 |
