EC Number   |
General Information |
Reference |
|---|
   3.1.21.7 | malfunction |
RNAi-mediated depletion of TbEndoV results in moderate growth defects in procyclic cells while the two EndoV alleles can be readily knocked out in bloodstream forms |
-, 752230 |
| 3.1.21.7 | malfunction |
RNAi-mediated depletion of TbEndoV results in moderate growth defects in procyclic cells while the two EndoV alleles can be readily knocked out in bloodstream forms. The enzyme has an important role in RNA metabolism in procyclic forms of the parasite |
-, 752230 |
| 3.1.21.7 | metabolism |
this DNA repair enzyme is also involved in RNA metabolism |
725322 |
| 3.1.21.7 | more |
the deoxyinosine-containing heteroduplex is added to a purified system consisting of soluble endonuclease V fusion protein, DNA polymerase I, and DNA ligase, along with the four deoxynucleoside triphosphates. The three proteins alone are sufficient to process the dI lesion efficiently, and the 3'-exonuclease activity of DNA polymerase I is sufficient to remove the dI lesion in this minimum reconstituted assay, overview |
714813 |
| 3.1.21.7 | physiological function |
adenine bases in DNA, RNA, and nucleotides are deaminated during normal metabolism via hydrolytic and nitrosative reactions. In RNA, the deaminated product inosine is resolved by human endonuclease V |
750545 |
| 3.1.21.7 | physiological function |
DNA polymerase I proofreading exonuclease activity is required for endonuclease V repair pathway |
-, 750391 |
| 3.1.21.7 | physiological function |
DNA repair enzyme, may also be involved in RNA metabolism |
725322 |
| 3.1.21.7 | physiological function |
endonuclease V has an important role in RNA metabolism in procyclic forms of the parasite |
-, 752230 |
| 3.1.21.7 | physiological function |
endonuclease V is an enzyme that initiates a conserved DNA repair pathway by making an endonucleolytic incision at the 3'-side 1 nt from a deaminated base lesion |
716390 |
| 3.1.21.7 | physiological function |
endonuclease V is an important enzyme for repairing deoxyinosine in DNA |
-, 750798 |
